CAY10762 |
| Catalog No.GC47060 |
An inhibitor of MAGL
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2514-37-6
Sample solution is provided at 25 µL, 10mM.
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CAY10762 is an inhibitor of monoacylglycerol lipase (MAGL; IC50 = 34.1 nM).1 It reduces hydrogen peroxide-induced lactate dehydrogenase (LDH) release from Neuro2a cells when used at a concentration of 1 µM. CAY10762 (10 mg/kg) increases levels of 2-arachidonoyl glycerol in mouse brain.
1.Castelli, R., Scalvini, L., Vacondio, F., et al.Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteinesJ. Med. Chem.63(3)1261-1280(2020)
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
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