Clavulanate lithium |
| Catalog No.GC38901 |
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Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 61177-44-4
Sample solution is provided at 25 µL, 10mM.
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Clavulanate lithium is a potent β-lactamase inhibitor and acts as an antibiotic[1][2].
Clavulanate lithium has weak antibacterial activity against most organisms when administered alone, but given in combination with beta-lactam antibiotics prevents antibiotic inactivation by microbial lactamase[1].Clavulanate lithium (0.25, 0.5 mg/L) causes a relatively slow inhibition of growth, and a higher concentration (1 mg/L) is only marginally more effective than 0.5 mg/L [2]. Cell Viability Assay[2] Cell Line: L. pneumophila NCTC 1119
[1]. Reading C, et al. Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus. Antimicrob Agents Chemother. 1977 May; 11(5): 852-857. [2]. Stokes DH, et al. Bactericidal effects of amoxycillin/clavulanic acid against intracellular Legionella pneumophila in tissue culture studies. J Antimicrob Chemother. 1989 Apr;23(4):547-56.
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