Daphnoretin |
| Catalog No.GC43377 |
Daphnoretin is a coumarin that has been found in W.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2034-69-7
Sample solution is provided at 25 µL, 10mM.
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Daphnoretin is a coumarin that has been found in W. indica and has diverse biological activities. It induces aggregation of washed rabbit platelets (EC50 = 17.2 μM), an effect that is reversed by the protein kinase C (PKC) inhibitor staurosporine . Daphnoretin is active against respiratory syncytial virus (RSV) in a plaque reduction assay using HEp-2 cells (IC50 = 5.87 μg/ml). It halts the cell cycle at the G2/M phase, induces apoptosis, and inhibits proliferation of human osteosarcoma (HOS) cells (IC50 = 3.89 μM). Daphnoretin also reduces proliferation, invasion, and migration of HCT116 colon cancer cells in a concentration-dependent manner.
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
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