Desogestrel-13C2-d2 |
| Catalog No.GC49025 |
An internal standard for the quantification of desogestrel
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Desogestrel-13C2-d2 is intended for use as an internal standard for the quantification of desogestrel by GC- or LC-MS. Desogestrel is a synthetic progestogen.1 It inhibits ovulation and prevents fertilization in rabbits and mice. Desogestrel inhibits rhodamine 123 efflux, a measure of P-glycoprotein activity, ex vivo in human lymphocytes and CD8+ T cells in a dose-dependent manner.2 Formulations containing desogestrel have been used as oral contraceptives and for the treatment of polycystic ovary syndrome.
1.van der Vies, J., and de Visser, J.Endocrinological studies with desogestrelArzneimittelforschung33(2)231-236(1983) 2.FrÖhlich, M., Albermann, N., Sauer, A., et al.In vitro and ex vivo evidence for modulation of P-glycoprotein activity by progestinsBiochem. Pharmacol.68(12)2409-2416(2004)
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