>>Analytical Standards>>Dextromethorphan (hydrobromide hydrate)

Dextromethorphan (hydrobromide hydrate) (Synonyms: DXM, D-Methorphan)

Catalog No.GC43428

데스트로메토르판(DXM)은 레보르파놀, 코드인 및 모르핀과 구조적 유사성을 가진 우전회전 모르피난입니다.

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Dextromethorphan (hydrobromide hydrate) Chemical Structure

Cas No.: 6700-34-1

Size 가격 재고 수량
50mg
US$33.00
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100mg
US$63.00
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500mg
US$259.00
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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 1 publications

Description Chemical Properties Product Documents Related Products

Dextromethorphan (DXM) is a dextratrorotatory morphinan with structural similarity to levorphanol, codeine, and morphine. Because of its strong antitussive effects, dextromethorphan is widely used as a cough suppressant. However, it does not provoke opioid activity as is characteristic of several other morphine derivatives. DXM binds to and inhibits NMDA (IC50 = 0.55 μM) and nicotinic receptors (IC50s = 0.7-3.9 μM) and blocks receptor-gated and voltage-gated calcium channels (IC50 = 60 μM) and voltage-gated sodium channels (IC50 = 78 μM). DXM has been used in multimodal analgesic therapies for acute and neuropathic pain.

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