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Ethoprop (Synonyms: Ethoprophos)

Catalog No.GC46142

An organothiophosphate nematicide and insecticide

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Ethoprop Chemical Structure

Cas No.: 13194-48-4

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100mg
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500mg
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Sample solution is provided at 25 µL, 10mM.

Description of Ethoprop

Ethoprop is an organothiophosphate nematicide and insecticide.1,2,3 It decreases the infectivity of M. chitwoodi and M. hapla second-stage juveniles (EC50s = 5.6 and 6.8 μg/ml, respectively) and inhibits hatching of M. chitwoodi egg masses and M. chitwoodi and M. hapla free eggs (EC50s = 0.2, 46, and 83.3 μg/ml, respectively).2 Ethoprop (1.8 μg/g) decreases the number of M. chitwoodi nematodes in tomato roots when added to soil from fields without previous ethoprop exposure, but is biodegraded in soil from fields previously exposed to ethoprop. In field trials, it decreases the percentage of potato tubers damaged by wireworms when applied as granules in the planting furrow at a concentration of 3 kg AI/ha.3 Ethoprop is toxic to rats via oral administration and dermal contact (LD50s = 47 and 226 mg/kg, respectively) as well as inhalation (LD50 = 0.123 mg/L).1 It is also toxic to bluegill (LC50 = 0.32 mg/L). Formulations containing ethoprop have been used in the agricultural control of pests.

|2. Mojtahedi, H., Santo, G.S., and Pinkerton, J.N. Efficacy of ethoprop on Meloidogyne hapla and M. chitwoodi and enhanced biodegradation in soil. J. Nematol. 23(4), 372-379 (1991).|3. Stewart, K.M. Chemical control of wireworms (Elateridae) in potatoes. N. Z. J. Exp. Agr. 9(3-4), 357-362 (1981).|1. Authority, E.F.S. Conclusion regarding the peer review of the pesticide risk assessment of the active substance ethoprophos. EFSA Scientific Report 66, 1-72 (2006).

Chemical Properties of Ethoprop

Cas No. 13194-48-4 SDF
Synonyms Ethoprophos
Canonical SMILES CCCSP(SCCC)(OCC)=O
Formula C8H19O2PS2 M.Wt 242.3
Solubility DMF: 5mg/mL,DMSO: 5mg/mL,Ethanol: 1.6mg/mL Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Ethoprop

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.1271 mL 20.6356 mL 41.2712 mL
5 mM 0.8254 mL 4.1271 mL 8.2542 mL
10 mM 0.4127 mL 2.0636 mL 4.1271 mL
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In vivo Formulation Calculator (Clear solution) of Ethoprop

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 5 reference(s) in Google Scholar.)

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