Flavokawain A (Synonyms: Flavokavain A, 4-methoxy Flavokawain B) |
| Catalog No.GC60845 |
유망한 항암제인 플라보카와인 A는 항종양 활성이 있는 카바 추출물의 칼콘입니다. Flavokawain A는 Bax 단백질 의존성 및 미토콘드리아 의존성 세포 사멸 경로의 관여에 의해 세포 사멸을 유도합니다. 플라보카와인 A는 방광암 연구의 가능성이 있습니다.
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Cas No.: 3420-72-2
Sample solution is provided at 25 µL, 10mM.
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Flavokawain A, a proming anticarcinogenic agent, is a chalcone from kava extract with anti-tumor activity. Flavokawain A induces cell apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway. Flavokawain A has the potential for the study of bladder cancer[1].
[1]. Xiaolin Zi, et al. Flavokawain A, a novel chalcone from kava extract, induces apoptosis in bladder cancer cells by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway and suppresses tumor growth in mice. Cancer Res. 2005 Apr 15;65(8):3479-86.
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