Cyclosporin A-Derivative 1 Free base |
Catalog No.GC35784 |
사이클로스포린 A-유도체 1(유리 염기)은 특허 WO 2013167703 A1에서 추출한 사이클로스포린 A의 개방에서 파생된 결정질 중간체입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 286852-20-8
Sample solution is provided at 25 µL, 10mM.
Cyclosporin A-Derivative 1 (Free base) is a crystalline intermediate derived from the opening of cyclosporin A extracted from patent WO 2013167703 A1. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.
Cyclosporin A-Derivative 1 is a non-immunosuppressive Cyclosporine A derivative. The cyclosporin is acylated on the butenyl-methyl-threonine side chain and then subjected to a ring-opening reaction (the ring opens between the sarcosine and the N-methyl-leucine residues). Cyclosporin A-Derivative 1 is a linear peptide intermediate[1].
[1]. Fabrice Gallou, et al. Process for the manufacture of cyclic undecapeptides. WO 2013167703 A1.
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