Eprodisate |
| Catalog No.GC35999 |
에프로디세이트는 아밀로이드 생성 단백질과 글리코사미노글리칸 간의 상호작용을 방해하여 아밀로이드 원섬유의 중합과 조직 내 원섬유 침착을 억제하도록 설계된 새로운 화합물입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 21668-77-9
Sample solution is provided at 25 µL, 10mM.
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Eprodisate is a new compound designed to interfere with interactions between amyloidogenic proteins and glycosaminoglycans and thereby inhibit polymerization of amyloid fibrils and deposition of the fibrils in tissues[1]. Eprodisate slow the progression of AA amyloidosis-related renal disease and has possible applicability to other types of amyloidosis[2].
[1]. Dember LM, et al. Eprodisate for the treatment of renal disease in AA amyloidosis. N Engl J Med. 2007 Jun 7;356(23):2349-60. [2]. Manenti L, et al. Eprodisate in amyloid A amyloidosis: a novel therapeutic approach• Expert Opin Pharmacother. 2008 Aug;9(12):2175-80.
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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