>>Signaling Pathways>> Angiogenesis>> PAR1>>GB-110

GB-110

Catalog No.GC36125

GB-110은 강력한 경구 활성 및 비펩티드 프로테아제 활성화 수용체 2(PAR2) 작용제입니다.

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GB-110 Chemical Structure

Cas No.: 1252806-70-4

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM[1]. Protease activated receptor 2[1]

[1]. Barry GD, et al. Novel agonists and antagonists for human protease activated receptor 2. J Med Chem. 2010 Oct 28;53(20):7428-40.

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Average Rating: 5 ★★★★★ (Based on Reviews and 8 reference(s) in Google Scholar.)

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