NQO1 activator 1 |
| Catalog No.GC36771 |
β-lapachone의 파생물인 NQO1 활성화제 1은 경구로 사용 가능한 NAD+ 조절제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1800405-30-4
Sample solution is provided at 25 µL, 10mM.
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NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. Elevated NAD+ levels triggers the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts[1]. NQO1[1]
[1]. Seo KS, et al. KL1333, a Novel NAD+ Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. Front Neurol. 2018 Jul 5;9:552.
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