Xanthohumol D |
| Catalog No.GC37939 |
홉에서 분리된 Xanthohumol D는 IC50 값이 110μM인 quinone reductase-2(QR-2)의 억제제이며 QR-2의 활성 부위에 결합합니다. Xanthohumol D는 시험관 내에서 인간 암 세포주에 대한 항증식 활성을 나타냅니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 274675-25-1
Sample solution is provided at 25 µL, 10mM.
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Xanthohumol D, isolated from hops, is an inhibitor of quinone reductase-2 (QR-2) with the IC50 value of 110 μM, and binds to the active site of QR-2. Xanthohumol D shows antiproliferative activity on human cancer cell lines in vitro[1][2]. IC50: 110 μM (Quinone reductase-2)[1]
[1]. Choi Y, et al. Screening natural products for inhibitors of quinone reductase-2 using ultrafiltration LC-MS. Anal Chem. 2011 Feb 1;83(3):1048-52. [2]. Tronina T, et al. Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro. Bioorg Med Chem. 2013 Apr 1;21(7):2001-6.
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