Uridine triacetate (Synonyms: PN401, RG2133, 2',3',5'-Tri-O-acetyluridine, Uridine Triacetate) |
| Catalog No.GC38302 |
우리딘 트리아세테이트(Tri-O-acetyl uridine)는 우리딘의 경구 활성 전구약물입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 4105-38-8
Sample solution is provided at 25 µL, 10mM.
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Uridine triacetate (Tri-O-acetyl uridine) is an orally active prodrug of Uridine. Uridine triacetate (Tri-O-acetyl uridine) is lipophilic, is quickly absorbed in the gut, and is rapidly deacetylated in the circulation to yield free uridine. Uridine triacetate (Tri-O-acetyl uridine) is uesd for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Uridine triacetate (Tri-O-acetyl uridine) delivers high concentrations of uridine, which competes with toxic 5-FU metabolites[1][2].
[1]. Ma WW, et al. Emergency use of uridine triacetate for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity. Cancer. 2017 Jan 1;123(2):345-356. [2]. Cada DJ, et al. Uridine Triacetate. Hosp Pharm. 2016 Jun;51(6):484-8.
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