Gunagratinib (Synonyms: ICP-192) |
| Catalog No.GC64875 |
구나그라티닙(ICP-192)은 공유 결합에 의해 비가역적으로 FGFR 활성을 강력하고 선택적으로 억제하는 저독성 및 경구 활성 pan-FGFR(섬유아세포 성장 인자 수용체) 억제제입니다. 구나그라티닙은 암 연구에 사용될 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2211082-53-8
Sample solution is provided at 25 µL, 10mM.
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Gunagratinib (ICP-192) is a low toxicity and orally active pan-FGFR (fibroblast growth factor receptors) inhibitor that potently and selectively inhibits FGFR activities irreversibly by covalent binding. Gunagratinib can be used for the research of cancer[1].
Gunagratinib (ICP-192) is a low toxicity and orally active pan-FGFR (fibroblast growth factor receptors) inhibitor that potently and selectively inhibits FGFR activities irreversibly by covalent binding[1].
[1]. Guo Ye, et al. Phase I result of ICP-192 (gunagratinib), a highly selective irreversible FGFR inhibitor, in patients with advanced solid tumors harboring FGFR pathway alterations. Journal of Clinical Oncology 39, no. 15_suppl (May 20, 2021) 4092-4092.
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