icFSP1 |
| Catalog No.GC26263 |
icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1115910-36-5
Sample solution is provided at 25 µL, 10mM.
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icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1].
References:
[1]. Toshitaka Nakamura, et al. Phase separation of FSP1 promotes ferroptosis. Nature. 2023 Jul;619(7969):371-377.
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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