L-Azatyrosine |
| Catalog No.GC67542 |
L-Azatyrosine은 Streptomyces chibaensis에서 분리한 항종양 항생제입니다. 821d96072c2d58d8970e76f526b0f6b8L-Azatyrosine은 발암성 Ras 유전자를 지닌 형질전환된 세포에 정상적인 표현형 행동을 회복시킬 수 있습니다.821d96072c2d58d8970e76f526b0f6b8
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 58525-82-9
Sample solution is provided at 25 µL, 10mM.
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L-Azatyrosine is an antitumor antibiotic isolated from Streptomyces chibaensis. L-Azatyrosine can restore normal phenotypic behavior to transformed cells bearing oncogenic Ras genes[1][2].
[1]. Adamczyk M, et, al. Enantioselective synthesis of (2-pyridyl)alanines via catalytic hydrogenation and application to the synthesis of L-azatyrosine. Org Lett. 2001 Oct 4;3(20):3157-9.
[2]. Shindo-Okada N, et, al. Permanent conversion of mouse and human cells transformed by activated ras or raf genes to apparently normal cells by treatment with the antibiotic azatyrosine. Mol Carcinog. 1989;2(3):159-67.
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