MC-Val-Cit-PAB-NH-C2-NH-Boc |
| Catalog No.GC64087 |
MC-Val-Cit-PAB-NH-C2-NH-Boc는 항체-약물 접합체(ADC) 합성에 사용되는 카텝신 절단 가능한 ADC 링커입니다.
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Cas No.: 1616727-22-0
Sample solution is provided at 25 µL, 10mM.
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MC-Val-Cit-PAB-NH-C2-NH-Boc is a cathepsin cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Akaiwa M, et al. Synthesis and Evaluation of Linear and Macrocyclic Dolastatin 10 Analogues Containing Pyrrolidine Ring Modifications. ACS Omega. 2018;3(5):5212-5221.
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