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Mergetpa

Catalog No.GC72702 Copy One-Click Copy Product Info

Mergetpa는 펩타이드와 B2 수용체 옹색제가 C 말단 아르기닌이 결핍된 대사물로 전환되는 것을 차단하는 카르복실펩타이드 효소 억제제이다.

Products are for research use only. Not for human use. We do not sell to patients.

Mergetpa Chemical Structure

Cas No.: 77102-28-4

Size 가격 재고 수량
5 mg
US$250.00
재고 있음
10 mg
US$401.00
재고 있음
25 mg
US$806.00
재고 있음

Tel:(909) 407-4943 Email: sales@glpbio.com


고객 리뷰

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Mergetpa

Mergetpa is a carboxypeptidase inhibitor used to block the conversion of kinins and B2 receptor antagonists to metabolites lacking the C-terminal arginine.

References:
[1]. D Regoli, et al. Conversion of kinins and their antagonists into B1 receptor activators and blockers in isolated vessels. Eur J Pharmacol. 1986 Aug 15;127(3):219-24.

Chemical Properties of Mergetpa

Cas No. 77102-28-4 SDF
Formula C7H15N3O2S2 M.Wt 237.34
Solubility H2O : 15 mg/mL (63.20 mM; Need ultrasonic) Storage 4°C, stored under nitrogen, away from moisture
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Mergetpa

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.2134 mL 21.0668 mL 42.1336 mL
5 mM 842.7 μL 4.2134 mL 8.4267 mL
10 mM 421.3 μL 2.1067 mL 4.2134 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Mergetpa

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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리뷰

Review for Mergetpa

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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