>>Signaling Pathways>> Microbiology & Virology>> Antibiotic>>MptpB-IN-1

MptpB-IN-1

Catalog No.GC64709

MptpB-IN-1(화합물 13)은 MptpB의 강력한 경구 활성 억제제입니다.

Products are for research use only. Not for human use. We do not sell to patients.

MptpB-IN-1 Chemical Structure

Cas No.: 2244622-44-2

Size 가격 재고 수량
5 mg
US$405.00
재고 있음
10 mg
US$720.00
재고 있음
25 mg
US$1,485.00
재고 있음
50 mg
US$2,295.00
재고 있음
100 mg
US$3,420.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

MptpB-IN-1 (Compound 13) is a potent and orally active inhibitor of MptpB. Mycobacterium tuberculosis protein-tyrosine-phosphatase B (MptpB) is a secreted virulence factor that subverts antimicrobial activity in the host. MptpB-IN-1 reduces multidrug-resistant mycobacterium tuberculosis survival and infection burden[1].

[1]. Vickers CF, et al. Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo. J Med Chem. 2018;61(18):8337-8352.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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