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NaPi2b-IN-2

Catalog No.GC70944 Copy One-Click Copy Product Info

NaPi2b-IN-2(화합물5)는 나트륨 의존성 트랜스퍼 단백질 2b(SLC34A2, NaPi2b)의 강력한 억제제로, 대인 NaPi2b의 IC50은 38nM이다.

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NaPi2b-IN-2 Chemical Structure

Cas No.: 2227445-31-8

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$1,511.00
재고 있음
1 mg
US$383.00
재고 있음
5 mg
US$843.00
재고 있음

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고객 리뷰

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of NaPi2b-IN-2

NaPi2b-IN-2 (compound 5) is a potent inhibitor of sodium-dependent transport protein 2b (SLC34A2, NaPi2b), with an IC50 of 38 nM for human NaPi2b. NaPi2b-IN-2 can be used for the research of hyperphosphatemia.

Chemical Properties of NaPi2b-IN-2

Cas No. 2227445-31-8 SDF
Formula C41H47ClF3N5O5S M.Wt 814.36
Solubility DMSO : 100 mg/mL (122.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) Storage -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of NaPi2b-IN-2

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.228 mL 6.1398 mL 12.2796 mL
5 mM 245.6 μL 1.228 mL 2.4559 mL
10 mM 122.8 μL 614 μL 1.228 mL
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In vivo Formulation Calculator (Clear solution) of NaPi2b-IN-2

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for NaPi2b-IN-2

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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