NIBR189 |
| Catalog No.GC15430 |
NIBR189는 EBI2(Epstein-Barr 바이러스 유도 유전자 2) 길항제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1599432-08-2
Sample solution is provided at 25 µL, 10mM.
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NIBR189 is a small molecule antagonist of the Epstein-Barr virus-induced gene 2 (EBI2; GPR183) receptor with IC50 of 16 nM(Binding) and 11 nM (Functional).IC50 value: 16/11 nM(Binding/Functional IC50) [1]Target: EBI2/GPR183 antagonistNIBR189 is a potent and selective EBI2 antagonist with improved pharmacokinetic properties which will help to probe the physiological function of EBI2 in health and disease.
References:
[1]. Gessier F, et al. Identification and characterization of small molecule modulators of the Epstein-Barr virus-induced gene 2 (EBI2) receptor. J Med Chem. 2014 Apr 24;57(8):3358-68.
Average Rating: 5 (Based on Reviews and 13 reference(s) in Google Scholar.)
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