Pentapeptide-18 (acetate) (Synonyms: Ala2,Leu5-Enkephalin, D-Ala2Leucine-Enkephalin, Tyr-D-Ala-Gly-Phe-Leu-OH) |
Catalog No.GC49705 |
A peptide derivative of enkephalin
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
Pentapeptide-18 is a peptide derivative of enkephalin.1,2 It reduces tail pinch-induced hyperalgesia in rats.2 Formulations containing pentapeptide-18 have been used in cosmeceuticals.
1.Beddell, C.R., Clark, R.B., Hardy, G.W., et al.Structural requirements for opioid activity of analogues of the enkephalinsProc. R. Soc. Long. B. Biol. Sci.198(1132)249-265(1977) 2.Maeda, M., Kawasaki, K., Mayumi, T., et al.Amino acids and peptides. XXII. Preparation and antinociceptive effect of [D-Ala2]Leu-enkephalin-poly(ethylene glycol) hybridBiol. Pharm. Bull.17(6)823-825(1994)
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