>>Signaling Pathways>> Proteases>> Ser/Thr Protease>>PKR-IN-C51

PKR-IN-C51

Catalog No.GC64483

PKR-IN-C51(화합물 51)은 9μM의 IC50을 갖는 ATP-경쟁 이중 가닥 RNA-활성화 단백질 키나제(PKR) 억제제입니다.

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PKR-IN-C51 Chemical Structure

Cas No.: 1314594-23-4

Size 가격 재고 수량
5 mg
US$144.00
재고 있음
10 mg
US$234.00
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25 mg
US$450.00
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50 mg
US$720.00
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100 mg
US$1,170.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

PKR-IN-C51(compound 51) is an ATP-competitive double-stranded RNA-activated protein kinase (PKR) inhibitor with an IC50 of 9 μM. PKR-IN-C51 inhibits intracellular PKR activation in a dose-dependent manner in primary mouse macrophages[1].

[1]. Ruslana Bryk, et al. Identification of new inhibitors of protein kinase R guided by statistical modeling. Bioorg Med Chem Lett. 2011 Jul 1;21(13):4108-14.

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