Prostaglandin E1-d4 (Synonyms: Alprostadild4, PGE1d4) |
Catalog No.GC47991
One-Click Copy Product Info
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An internal standard for the quantification of prostaglandin E1
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 211105-33-8
Sample solution is provided at 25 µL, 10mM.
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Prostaglandin E1-
1.Cawello, W., Schweer, H., Dietrich, B., et al.Pharmacokinetics of prostaglandin E1 and its main metabolites after intracavernous injection and short-term infusion of prostaglandin E1 in patients with erectile dysfunctionJournal of Urology1581403-1407(1997) 2.Kobzar, G., Mardla, V., JÄrving, I., et al.Antiaggregating potency of E-type prostaglandins in human and rabbit plateletsProceedings of the Estonian Academy of Sciences.Chemistry40179-180(1991) 3.Okada, F., Nukada, T., Yamauchi, Y., et al.The hypotensive effect of prostaglandin E1 on hypertensive cases of various typesProstaglandins799-106(1974) 4.Padma-Nathan, H., Hellstrom, W.J.G., Kaiser, F.E., et al.Treatment of men with erectile dysfunction with transurethral alprostadilNew England Journal of Medicine3361-7(1997) 5.Olley, P.M., and Coceani, F.Prostaglandins and the ductus arteriosusAnnual Reviews of Medicine32375-3785(1981)
| Cas No. | 211105-33-8 | SDF | |
| Synonyms | Alprostadild4, PGE1d4 | ||
| Canonical SMILES | CCCCC[C@@H](O)/C=C/[C@H]([C@H]1CCCC([2H])([2H])C([2H])([2H])CC(O)=O)[C@H](O)CC1=O | ||
| Formula | C20H30D4O5 | M.Wt | 358.5 |
| Solubility | DMF: >100 mg/ml (from PGE1),DMSO: >50 mg/ml (from PGE1),Ethanol: >50 mg/ml (from PGE1),PBS pH 7.2: >1.6 mg/ml (from PGE1) | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 2.7894 mL | 13.947 mL | 27.894 mL |
| 5 mM | 557.9 μL | 2.7894 mL | 5.5788 mL |
| 10 mM | 278.9 μL | 1.3947 mL | 2.7894 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >99.00% Appearance: A solution in methyl acetate
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 18 reference(s) in Google Scholar.)