SC-VC-PAB-MMAE |
| Catalog No.GC39436 |
SC-VC-PAB-MMAE는 절단 가능한 링커 SC-VC-PAB를 통해 연결된 항유사분열제인 모노메틸 아우리스타틴 E(MMAE, 튜불린 억제제)를 사용하여 강력한 항종양 활성을 갖는 ADC용 약물-링커 접합체입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2259318-46-0
Sample solution is provided at 25 µL, 10mM.
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SC-VC-PAB-MMAE is a drug-linker conjugate for ADC with potent antitumor activity by using the anti-mitotic agent, monomethyl auristatin E (MMAE, a tubulin inhibitor), linked via the cleavable linker SC-VC-PAB[1].
[1]. Brian Lannutti, et al. Ror1 antibody immunoconjugates. WO2018237335A1.
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