SNIPER(ABL)-020 |
| Catalog No.GC65592 |
SNIPER(ABL)-020은 다사티닙(ABL 억제제)과 베스타틴(IAP 리간드)을 링커로 결합시켜 BCR-ABL 단백질의 감소를 유도한다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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SNIPER(ABL)-020, conjugating Dasatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein[1].
[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.
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Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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