SPDP-C6-NHS ester |
| Catalog No.GC61575 |
SPDP-C6-NHS 에스테르는 PROTAC 합성에 사용할 수 있는 알킬/에테르 기반 PROTAC 링커입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 158913-22-5
Sample solution is provided at 25 µL, 10mM.
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SPDP-C6-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Average Rating: 5 (Based on Reviews and 17 reference(s) in Google Scholar.)
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