>>Signaling Pathways>> Proteases>> Endogenous Metabolite>>Taurocholic acid (N-Choloyltaurine)

Taurocholic acid (N-Choloyltaurine) (Synonyms: Ethanesulfonic Acid, TCA)

Catalog No.GC33648 Copy One-Click Copy Product Info

타우로콜산(N-Choloyltaurine)(N-Choloyltaurine)은 지방의 유화에 관여하는 담즙산입니다.

Products are for research use only. Not for human use. We do not sell to patients.

Taurocholic acid (N-Choloyltaurine) Chemical Structure

Cas No.: 81-24-3

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$71.00
재고 있음
5mg
US$63.00
재고 있음
10mg
US$108.00
재고 있음
25mg
US$225.00
재고 있음

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고객 리뷰

Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of Taurocholic acid (N-Choloyltaurine)

Taurocholic acid is a bile acid involved in the emulsification of fats.

The bile acid Taurocholic acid (TCA) exerts permeation enhancing effects in vivo[1].

[1]. Mooranian A, et al. The effect of a tertiary bile acid, taurocholic acid, on the morphology and physical characteristics of microencapsulated probucol: potential applications in diabetes: a characterization study. Drug Deliv Transl Res. 2015 Oct;5(5):511-22.

Chemical Properties of Taurocholic acid (N-Choloyltaurine)

Cas No. 81-24-3 SDF
Synonyms Ethanesulfonic Acid, TCA
Canonical SMILES C[C@H](CCC(NCCS(=O)(O)=O)=O)[C@@]1(C)CC[C@@]2(C)[C@]3(C)[C@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@]3(C)C[C@H](O)[C@]12C
Formula C30H53NO7S M.Wt 571.81
Solubility DMSO : 100 mg/mL (193.91 mM; Need ultrasonic); H2O : 100 mg/mL (193.91 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Taurocholic acid (N-Choloyltaurine)

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 1.7488 mL 8.7442 mL 17.4883 mL
5 mM 349.8 μL 1.7488 mL 3.4977 mL
10 mM 174.9 μL 874.4 μL 1.7488 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Taurocholic acid (N-Choloyltaurine)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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리뷰

Review for Taurocholic acid (N-Choloyltaurine)

Average Rating: 5 ★★★★★ (Based on Reviews and 37 reference(s) in Google Scholar.)

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