Vafidemstat (ORY-2001) (Synonyms: ORY-2001) |
| Catalog No.GC31101 |
Vafidemstat(ORY-2001)(ORY-2001)은 경구, 뇌 침투, 이중 라이신 특이적 히스톤 데메틸라제(LSD1)/MAO-B 억제제입니다.
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Cas No.: 1357362-02-7
Sample solution is provided at 25 µL, 10mM.
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Vafidemstat (ORY-2001) is a dual lysine-specific histone demethylase (LSD1)/MAO-B inhibitor.
Vafidemstat (ORY-2001), a dual LSD1/MAO-B inhibitor, is a novel epigenetic agent for the treatment of neurodegenerative diseases. LSD1 is a protein that participates in transcription regulation complexes; its modulation can be used to tweak transcriptional imbalances in neurodegenerative disease and redress neuroinflammation and cognitive deficit[1]. Vafidemstat (ORY-2001) can be used in the treatment of Alzheimer's disease[2].
[1]. ORYZON presents data on the Phase I trial with ORY-2001 at the 13th International Conference on Alzheimer's and Parkinson's diseases [2]. ORYZON Reports Financial Results and Corporate Update for the 1st Half Ended June 30, 2018.
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