VU0080241 |
| Catalog No.GC61851 |
VU0080241은 4.6μM의 EC50을 갖는 대사성 글루타메이트 수용체 아형 4(mGluR4)의 양성 알로스테릭 조절제(PAM)입니다.
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Cas No.: 393845-24-4
Sample solution is provided at 25 µL, 10mM.
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VU0080241 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 4 (mGluR4), with an EC50 of 4.6 µM[1].
References:
[1]. Colleen M Niswender, et al. Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulators. Bioorg Med Chem Lett. 2008 Oct 15; 18(20): 5626-5630.
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