Yuanhuacine |
| Catalog No.GC60389 |
Yuanhuacine(Gnidilatidin), Daphne genkwa의 꽃에서 추출한 다프난 디테르페노이드(daphnane diterpenoid)로 광범위한 항종양 활성이 있습니다. Yuanhuacin은 경구 활성을 가진 DNA 손상 물질입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 60195-70-2
Sample solution is provided at 25 µL, 10mM.
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Yuanhuacine (Gnidilatidin), a daphnane diterpenoid from the flowers of Daphne genkwa with extensive anti-tumor activity. Yuanhuacine is a DNA-damaging agent with orally active[1][2].
[1]. Ji In Kang, et al. Anti-Tumor Activity of Yuanhuacine by Regulating AMPK/mTOR Signaling Pathway and Actin Cytoskeleton Organization in Non-Small Cell Lung Cancer Cells. PLoS One. 2015 Dec 11;10(12):e0144368. [2]. Ruowen Zhang, et al. The Chinese herb isolate yuanhuacine (YHL-14) induces G2/M arrest in human cancer cells by up-regulating p21 protein expression through an p53 protein-independent cascade. J Biol Chem. 2014 Mar 7;289(10):6394-403.
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
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