Cell Cycle/Checkpoint
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.
Research Areas
- ATM/ATR(28)
- Aurora Kinase(35)
- Cdc42(4)
- Cdc7(3)
- Chk(13)
- c-Myc(52)
- CRM1(10)
- Cyclin-Dependent Kinases(70)
- E1 enzyme(1)
- G-quadruplex(16)
- Haspin(6)
- HMTase(1)
- Kinesin(32)
- Ksp(4)
- Microtubule/Tubulin(301)
- Mps1(17)
- Mitotic(7)
- RAD51(13)
- ROCK(76)
- Rho(13)
- PERK(22)
- PLK(51)
- PTEN(7)
- Wee1(16)
- PAK(29)
- Arp2/3 Complex(10)
- Dynamin(18)
- ECM & Adhesion Molecules(53)
- Cholesterol Metabolism(10)
- Endomembrane System & Vesicular Trafficking(34)
- G1(50)
- G2/M(35)
- G2/S(16)
- Genotoxic Stress(22)
- Inositol Phosphates(65)
- Proteolysis(179)
- Cytoskeleton & Motor Proteins(71)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(2)
- MARK(4)
- NEKs(9)
- ATF6(2)
- ClpP(6)
- Disulfidptosis(1)
- HMG Family(1)
- PDI(1)
- SWI/SNF Complex(7)
- VISTA(4)
- HOXA(1)
Products Related to Cell Cycle/Checkpoint(1540)
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC12642 | THZ1 Hydrochloride | 1604810-83-4 | >98.00% | |
CDK7 inhibitor | ||||
| GC13869 | Fasudil | 103745-39-7 | >98.00% | |
Fasudil (HA-1077; AT877) is a non-specific RhoA/ROCK inhibitor with a K i of 0.33μM and an IC 50 of 0.158μM for ROCK1, and IC 50 of 4.58μM, 12.30μM, and 1.650μM for ROCK2, PKA, PKC, and PKG, respectively. | ||||
| GC14735 | Poloxime | 17302-61-3 | >98.00% | |
polo-like kinase 1 （PLK) analogue | ||||
| GC15914 | CDK7-IN-1 | 1604810-84-5 | - | |
potent and selective CDK7 inhibitor | ||||