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ROCK

ROCK (Rho-associated protein kinase) is a kinase belonging to the AGC family of serine-threonine kinases and takes part in regulating the shape and movement of cells by acting on the cytoskeleton.

Products for  ROCK

  1. Cat.No. Product Name Information
  2. GC41737 (S)-Glycyl-H-1152 (hydrochloride) Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. (S)-Glycyl-H-1152 (hydrochloride)  Chemical Structure
  3. GC12314 3-(4-Pyridyl)indole ROCK-I inhibitor 3-(4-Pyridyl)indole  Chemical Structure
  4. GC16475 Afuresertib pan-AKT inhibitor Afuresertib  Chemical Structure
  5. GC42747 Afuresertib (hydrochloride) Afuresertib is a selective, orally bioavailable inhibitor of Akt1, 2, and 3 with Ki values of 0.08, 2, and 2.6 nM, respectively. Afuresertib (hydrochloride)  Chemical Structure
  6. GC34300 AR-13324 analog mesylate AR-13324 analog mesylate  Chemical Structure
  7. GC19034 AR-13324 mesylate AR-13324 is a small-molecule inhibitor of Rho kinase and a norepinephrine transporter; reduces intraocular pressure (IOP) in normotensive monkey eyes. AR-13324 mesylate  Chemical Structure
  8. GC17712 AT13148 Multi-AGC kinase inhibitor,ATP-competitive AT13148  Chemical Structure
  9. GC35442 Azaindole 1 Azaindole 1  Chemical Structure
  10. GC32868 BDP5290 BDP5290  Chemical Structure
  11. GC38898 CCG-222740 CCG-222740  Chemical Structure
  12. GC16097 chroman 1 ROCK II inhibitor, highly potent and selective chroman 1  Chemical Structure
  13. GC43286 CMPD101 A GRK2 and GRK3 inhibitor CMPD101  Chemical Structure
  14. GC63333 Cotosudil Cotosudil  Chemical Structure
  15. GC45414 CRT0066854   CRT0066854  Chemical Structure
  16. GC13869 Fasudil Calcium antagonist Fasudil  Chemical Structure
  17. GC14289 Fasudil (HA-1077) HCl Protein kinase inhibitor Fasudil (HA-1077) HCl  Chemical Structure
  18. GC38791 GSK-25 GSK-25  Chemical Structure
  19. GC19177 GSK180736A GSK180736A is a G protein-coupled receptor kinase 2 (GRK2) inhibitor with an IC50 of 0.77 uM. GSK180736A  Chemical Structure
  20. GC17936 GSK269962A ROCK inhibitor GSK269962A  Chemical Structure
  21. GC18119 GSK429286A Selective ROCK1/ROCK2 inhibitor GSK429286A  Chemical Structure
  22. GC36207 H-1152 H-1152  Chemical Structure
  23. GC36208 H-1152 dihydrochloride H-1152 dihydrochloride  Chemical Structure
  24. GC43803 HA-1077 (hydrochloride) Rho-associated kinase (ROCK), an effector of the small GTP-binding protein Rho, plays an important role in various cellular functions including vascular smooth muscle contraction, proliferation, and migration as well as inflammatory cell mobility. HA-1077 (hydrochloride)  Chemical Structure
  25. GC10901 Hydroxyfasudil Rho-kinase inhibitor and vasodilator Hydroxyfasudil  Chemical Structure
  26. GC10338 Hydroxyfasudil hydrochloride Rho-kinase inhibitor and vasodilator Hydroxyfasudil hydrochloride  Chemical Structure
  27. GC12817 K-115

    Selective Rho kinase inhibitor

    K-115  Chemical Structure
  28. GC12402 LX7101 HCL Dual LIM-kinase and ROCK inhibitor LX7101 HCL  Chemical Structure
  29. GC12491 Narciclasine Modulates the Rho/ROCK/LIM kinase/cofilin pathway Narciclasine  Chemical Structure
  30. GC10716 Netarsudil (AR-13324) ROCK inhibitor Netarsudil (AR-13324)  Chemical Structure
  31. GC50116 OXA 06 dihydrochloride Potent ROCK inhibitor OXA 06 dihydrochloride  Chemical Structure
  32. GC33310 Rho-Kinase-IN-1 Rho-Kinase-IN-1  Chemical Structure
  33. GC37534 Ripasudil free base Ripasudil free base  Chemical Structure
  34. GC50092 RKI 1447 dihydrochloride Potent and selective ROCK inhibitor; antitumor RKI 1447 dihydrochloride  Chemical Structure
  35. GC44847 RKI-1313 RKI-1313  Chemical Structure
  36. GC15437 RKI-1447 Potent ROCK1/ROCK2 inhibitor RKI-1447  Chemical Structure
  37. GC37551 ROCK inhibitor-2 ROCK inhibitor-2  Chemical Structure
  38. GC31952 ROCK-IN-1 ROCK-IN-1  Chemical Structure
  39. GC31883 ROCK2-IN-2 ROCK2-IN-2  Chemical Structure
  40. GC13759 SAR407899 ATP-competitive ROCK inhibitor SAR407899  Chemical Structure
  41. GC16289 SAR407899 hydrochloride ATP-competitive ROCK inhibitor SAR407899 hydrochloride  Chemical Structure
  42. GC15170 SB 772077B dihydrochloride Rho-kinase (ROCK) inhibitor SB 772077B dihydrochloride  Chemical Structure
  43. GC12827 SLx-2119 Selective ROCK2 inhibitor SLx-2119  Chemical Structure
  44. GC63351 Sovesudil Sovesudil  Chemical Structure
  45. GC63716 Sovesudil hydrochloride Sovesudil hydrochloride  Chemical Structure
  46. GC50043 SR 3677 dihydrochloride Potent, selective Rho-kinase (ROCK) inhibitor SR 3677 dihydrochloride  Chemical Structure
  47. GC10722 SR-3677 Rho Kinase (ROCK-II) inhibitor SR-3677  Chemical Structure
  48. GC11181 Thiazovivin ROCK inhibitor Thiazovivin  Chemical Structure
  49. GC63253 Verosudil Verosudil  Chemical Structure
  50. GC15712 Y-27632 A ROCK inhibitor,potent and selective Y-27632  Chemical Structure
  51. GC10512 Y-27632 dihydrochloride A ROCK1 inhibitor Y-27632 dihydrochloride  Chemical Structure
  52. GC37947 Y-33075 Y-33075  Chemical Structure
  53. GC13423 Y-39983 dihydrochloride ROCK family inhibitor Y-39983 dihydrochloride  Chemical Structure
  54. GC33120 ZINC00881524 ZINC00881524  Chemical Structure

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