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Home >> Signaling Pathways >> Cell Cycle/Checkpoint >> RAD51

RAD51

RAD51 is a protein that contributed to homologous recombination and DSB (DNA double-strand break) repair in the DNA damage response pathway. It is associated with genome instablility and tumorgenesis.

Products for  RAD51

  1. Cat.No. Product Name Information
  2. GC16391 Amuvatinib (MP-470, HPK 56) A multi-targeted RTK inhibitor Amuvatinib (MP-470, HPK 56) Chemical Structure
  3. GC33362 Amuvatinib hydrochloride (MP470 hydrochloride) Amuvatinib hydrochloride (MP470 hydrochloride) (MP470 hydrochloride) is an orally bioavailable multi-targeted tyrosine kinase inhibitor with potent activity against mutant c-Kit, PDGFRα, Flt3, c-Met and c-Ret. Amuvatinib hydrochloride (MP470 hydrochloride) (MP470 hydrochloride) is also a DNA repair suppressor through suppression of DNA repair protein RAD51, thereby disrupting DNA damage repair. Antineoplastic activity. Amuvatinib hydrochloride (MP470 hydrochloride) Chemical Structure
  4. GC62128 Bractoppin Bractoppin is a inhibitor of phosphopeptide recognition by the human BRCA1 tBRCT domain with IC50 of 74 nM. Bractoppin Chemical Structure
  5. GC65935 CAM833 CAM833 is a potent orthosteric inhibitor of the interaction between BRCA2 and RAD51 with a Kd of 366 nM against the ChimRAD51 protein. CAM833 also inhibits RAD51 oligomerization. CAM833 Chemical Structure
  6. GC32912 IBR2 IBR2 is a potent and specific RAD51 inhibitor and inhibits RAD51-mediated DNA double-strand break repair. IBR2 disrupts RAD51 multimerization, accelerates proteasome-mediated RAD51 protein degradation, inhibits cancer cell growth and induces apoptosis. IBR2 Chemical Structure
  7. GC19306 RAD51 Inhibitor B02 RAD51 Inhibitor B02 (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 uM. RAD51 Inhibitor B02 Chemical Structure
  8. GC63165 RAD51-IN-1 RAD51-IN-1, a derivative of ?B02, is a potent inhibitor of RAD51. RAD51-IN-1 can be used for cancer research. RAD51-IN-1 Chemical Structure
  9. GC65383 RAD51-IN-2 RAD51-IN-2 (compound example 67A) is a RAD51 inhibitor extracted from patent WO2019/051465A1. RAD51-IN-2 Chemical Structure
  10. GC68416 RAD51-IN-3 RAD51-IN-3 Chemical Structure
  11. GC67888 RAD51-IN-5 RAD51-IN-5 Chemical Structure
  12. GC18140 RI-1 A RAD51 inhibitor RI-1 Chemical Structure
  13. GC12752 RI-2 Optimized reversible RAD51 inhibitor RI-2 Chemical Structure
  14. GC16265 RS-1 RAD51 activator RS-1 Chemical Structure

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