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Home >> Signaling Pathways >> Cell Cycle/Checkpoint >> Kinesin

Kinesin

Kinesin is a protein belonging to a class of motor proteins found in eukaryotic cells.

Products for  Kinesin

  1. Cat.No. Product Name Information
  2. GC16472 ARQ 621

    Eg5 inhibitor

     ARQ 621 Chemical Structure
  3. GC11656 ARRY 520 trifluoroacetate

    Filanesib

     A potent Eg5 inhibitor ARRY 520 trifluoroacetate Chemical Structure
  4. GC13282 ARRY-520 R enantiomer ARRY-520 R enantiomer Chemical Structure
  5. GC18956 AZ82

    AZ82 is a small molecule inhibitor of KIFC1/HSET, a kinesin-14 family protein that is important for assembling bipolar spindles in cancer cells containing supernumerary centrosomes.

     AZ82 Chemical Structure
  6. GC73016 AZD4877 AZD4877 is another isostere to Ispinesib and also a kinesin spindle protein (Eg5) inhibitor with IC50 of 2 nM. AZD4877 Chemical Structure
  7. GC48901 BRD9876 An Eg5 inhibitor BRD9876 Chemical Structure
  8. GC11252 CW069 allosteric inhibitor of HSET, selective CW069 Chemical Structure
  9. GC32969 Dimethylenastron An inhibitor of EG5 Dimethylenastron Chemical Structure
  10. GC35964 Eg5 Inhibitor V, trans-24 Eg5 Inhibitor V, trans-24 is a potent and specific kinesin Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer. Eg5 Inhibitor V, trans-24 Chemical Structure
  11. GC10681 Eg5-I potent inhibitor of Eg5 Eg5-I Chemical Structure
  12. GC18165 EMD534085

    Inhibitor of the mitotic kinesin-5

     EMD534085 Chemical Structure
  13. GC15659 GSK-923295

    GSK923295A

     An inhibitor of CENP-E GSK-923295 Chemical Structure
  14. GC60891 GW406108X

    GW108X

     GW406108X is a specific Kif15 (Kinesin-12) inhibitor with an IC50 of 0.82 uM in ATPase assays. GW406108X, a potent autophagy inhibitor, shows ATP competitive inhibition against ULK1 with a pIC50 of 6.37 (427 nM). GW406108X inhibits ULK1 kinase activity and blocks autophagic flux, without affecting the upstream signaling kinases mTORC1 and AMPK. GW406108X Chemical Structure
  15. GC13394 Ispinesib (SB-715992)

    SB-715992

     Ispinesib (SB-715992) is a specific inhibitor of kinesin spindle protein (KSP), with a Ki app of 1.7 nM. Ispinesib (SB-715992) Chemical Structure
  16. GC16167 K 858 K858 Racemic is an ATP-uncompetitive inhibitor of kinesin Eg5 with an IC50 of 1.3 μM. K 858 Chemical Structure
  17. GC16603 Kif15-IN-1 potent Kif15 kinesin inhibitor Kif15-IN-1 Chemical Structure
  18. GC17994 Kif15-IN-2 potent Kif15 kinesin inhibitor Kif15-IN-2 Chemical Structure
  19. GC31803 Litronesib (LY-2523355) Litronesib (LY-2523355) (LY2523355) is a selective mitosis-specific kinesin Eg5 inhibitor, with antitumor activity. Litronesib (LY-2523355) Chemical Structure
  20. GC30393 Litronesib Racemate (LY-2523355 Racemate)

    LY2523355 Racemate

     Litronesib Racemate (LY-2523355 Racemate) (LY2523355 Racemate) is the racemate of litronesib. Litronesib Racemate (LY-2523355 Racemate) Chemical Structure
  21. GC73869 MC-Val-Cit-PAB-Ispinesib MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent inhibitor of Eg5. MC-Val-Cit-PAB-Ispinesib Chemical Structure
  22. GC74159 MK-0731 MK-0731 is a selective, non-competitive and allosteric kinesin spindle protein (KSP) inhibitor with an IC50 of 2.2 nM and a pKa of 7.6. MK-0731 Chemical Structure
  23. GC14929 Monastrol

    (±)-Monastrol

    Eg5 inhibitor

     Monastrol Chemical Structure
  24. GC10083 MPI-0479605 Mps1 inhibitor,selective and ATP competitive MPI-0479605 Chemical Structure
  25. GC12788 Paprotrain

    Passenger Proteins Transport Inhibitor

    mitotic kinesin-like protein 2 (MKLP-2) inhibitor

     Paprotrain Chemical Structure
  26. GC34297 PF-2771 PF-2771 is a potent and selective centromere protein E (CENP-E) inhibitor, inhibiting CENP-E motor activity with an IC50 of 16.1 nM; PF-2771 is used as an anticancer agent. PF-2771 Chemical Structure
  27. GC72926 PVZB1194 PVZB1194 is a biphenyl-type inhibitor of Kinesin spindle protein Eg5 or KIF11. PVZB1194 Chemical Structure
  28. GC14600 SB743921 SB743921 is a potent inhibitor of the mitotic kinesin KSP (Eg5), with a Ki of 0.1 nM. SB743921 Chemical Structure

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