(±)-Nornicotine (Synonyms: DL-Nornicotine, (R,S)-Nornicotine) |
| Catalog No.GC41676 |
(±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 5746-86-1
Sample solution is provided at 25 µL, 10mM.
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(±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. The α6 and α7 subunit-containing neuronal nAChRs are particularly responsive to nornicotine with EC50 values of approximately 4 and 17 µM, respectively, when expressed in Xenopus oocytes. Nornicotine promotes cell migration and destabilizes cell-cell junctions in an endothelial cell line. It is generally thought to be free from abuse potential, but it has been self-administered by rats. It can be detected in urine.
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