Apraglutide TFA (Synonyms: FE 203799 TFA) |
| Catalog No.GC35376 |
Apraglutida TFA (FE 203799 TFA), un péptido sintético de 33 aminoÁcidos y un anÁlogo de GLP-2 de acciÓn prolongada, mejora la adaptaciÓn y el crecimiento intestinal lineal en un modelo de lechones recién nacidos con sÍndrome de intestino corto con resecciÓn total del Íleon .
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Apraglutide TFA (FE 203799 TFA), a synthetic 33-amino-acid peptide and a long-acting GLP-2 analogue, enhances adaptation and linear intestinal growth in a neonatal piglet model of short bowel syndrome with total resection of the ileum[1].
Apraglutide (FE 203799; 5 mg/kg/dose, subcutaneously, twice on days 0 and 4 postsurgery) treated piglets are healthy, have significant lower fecal fat and energy losses and exhibite intestinal lengthening, greater small-intestinal weight, longer villus height, and greater crypt depth on day 7[1]. Animal Model: NewbornDuroc piglets, 2-5 days old and weighing between 2-2.6 kg[1].
[1]. Slim GM, et al. Novel Long-Acting GLP-2 Analogue, FE 203799 (Apraglutide), Enhances Adaptation and Linear Intestinal Growth in a Neonatal Piglet Model of Short Bowel Syndrome with Total Resection of the Ileum. JPEN J Parenter Enteral Nutr. 2019 Jan 6.
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