MC-GGFG-DX8951 (Synonyms: MC-GGFG-DX8951) |
| Catalog No.GC39309 |
MC-GGFG-DX8951 (MC-GGFG-DX8951) is a drug-linker conjugate for ADC. MC-GGFG-DX8951 is a DX8951 (a DNA topoisomerase I inhibitor) derivative with protease cleavable MC-GGFG linker. MC-GGFG-DX8951 shows antitumor activity and can be used to prepare DX8951 antibody conjugate (ADC).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1600418-29-8
Sample solution is provided at 25 µL, 10mM.
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MC-GGFG-DX8951 is a drug-linker conjugate for ADC with antitumor activity by using DX8951 (a DNA topoisomerase I inhibitor), linked via the protease cleavable MC-GGFG linker[1].
[1]. Nakada T, et al. Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1542-1545.
Average Rating: 5 (Based on Reviews and 31 reference(s) in Google Scholar.)
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