PD 180970 |
| Catalog No.GC12637 |
PD 180970 es un inhibidor de la quinasa p210Bcr-Abl muy potente y competitivo con ATP, con una IC50 de 5 nM para inhibir la autofosforilación de p210Bcr-Abl.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 287204-45-9
Sample solution is provided at 25 µL, 10mM.
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ATP-competitive inhibitor of p210bcr/abl tyrosine kinase; selectively induces apoptosis in chronic myeloid leukemia (CML) K562 cells. Inhibits in vivo tyrosine phosphorylation of Gab2, CrkL and p210bcr/abl (IC50 values are 80, 80 and 170 nM respectively).
Review for PD 180970
Average Rating: 5 (Based on Reviews and 24 reference(s) in Google Scholar.)
Review for PD 180970
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