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PROTAC EZH2 Degrader-1

Catalog No.GC65509

PROTAC EZH2 Degrader-1 (Compuesto 150d), un potente PROTAC EZH2 Degrader, ejerce un efecto inhibidor sobre la actividad de la metiltransferasa de EZH2 con una IC50 de 2,7 nM. EZH2 juega un papel importante en muchos procesos de tumorigénesis y desarrollo.

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PROTAC EZH2 Degrader-1 Chemical Structure

Cas No.: 2641601-67-2

Tamaño Precio Disponibilidad Cantidad
5mg
585,00 $
Disponible
10mg
882,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

PROTAC EZH2 Degrader-1 (Compound 150d), a potent PROTAC EZH2 Degrader, exerts inhibitory effect on EZH2 methyltransferase activity with the IC50 of 2.7 nM. EZH2 plays an important role in many tumorigenesis and development processes[1].

[1]. Juan Xia, et al. Targeting Enhancer of Zeste Homolog 2 for the Treatment of Hematological Malignancies and Solid Tumors: Candidate Structure-Activity Relationships Insights and Evolution Prospects. J Med Chem. 2022 May 26;65(10):7016-7043.

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