DNA Damage/DNA Repair
Research Areas
- MTH1(4)
- PARP(115)
- ATM/ATR(33)
- DNA Alkylating(23)
- DNA Ligases(3)
- DNA Methyltransferase(29)
- DNA-PK(31)
- HDAC(158)
- Nucleoside Antimetabolite/Analogue(200)
- Telomerase(16)
- Topoisomerase(210)
- tankyrase(5)
- Antifolate(38)
- CDK(345)
- Checkpoint Kinase (Chk)(40)
- CRISPR/Cas9(9)
- Deubiquitinase(88)
- DNA Alkylator/Crosslinker(95)
- DNA/RNA Synthesis(615)
- Eukaryotic Initiation Factor (eIF)(34)
- IRE1(25)
- LIM Kinase (LIMK)(12)
- TOPK(6)
- Casein Kinase(63)
- DNA Intercalating Agents(8)
- DNA/RNA Oxidative Damage(13)
- Poly(ADP-ribose) Glycohydrolase (PARG)(6)
- Early 2 Factor (E2F)(2)
- Zinc Finger Protein(1)
Products Related to DNA Damage/DNA Repair(2131)
- GC81508Unylinker-OH Resin (Substitution:300±25 µmol/g)Purity: >98.00%
Unylinker-OH Resin (Substitution:300±25 µmol/g) is a macroporous polystyrene resin functionalized with Unylinker active groups with uniform particle size and uniform active groups.
- GC81509DMTr-2'-O-C22-rU-3'-CE-phosphoramiditeCAS: 2923115-86-8Purity: >98.00%
DMTr-2'-O-C22-rU-3'-CE-phosphoramidite is an RNA phosphoramidite monomer.
- GC81514PROTAC SMARCA2 degrader-35CAS: 3032998-97-0Purity: >98.00%
PROTAC SMARCA2 degrader-35 (Compound 43) is a selective SMARCA2 PROTAC degrader with a DC 50 < 0.1 μM for SMARCA2.
- GC815212',3'-ddA(N-Bz) PhosphoramiditePurity: >98.00%
2',3'-ddA(N-Bz) Phosphoramidite is a modified phosphoramidite monomer that can be used for the synthesis of oligonucleotides.
- GC81522WWZ-11-098Purity: >98.00%
WWZ-11-098 is a selective CDK6 PROTAC degrader with DC 50 of 2.6 nM.
- GC81527SofetabartCAS: 3066905-22-1Purity: >98.00%
Sofetabart (LY-4170156 Antibody) is a humanized IgG1 antibody that specifically targets folate receptor α ( FRα ).
- GC81528(5-Cl)-Exatecan TFAPurity: >98.00%
(5-Cl)-Exatecan TFA is a derivative of Exatecan and a DNA topoisomerase inhibitor.
- GC81530Elfetabart drozuntecanCAS: 3061153-84-9Purity: >98.00%
Elfetabart drozuntecan (DB-1311; BNT324) is an antibody-drug conjugate ( ADC ) targeting B7H3.
- GC81543GPX4-IN-19CAS: 3102894-57-2Purity: >99.00%
GPX4-IN-19 is an effective GPX4 inhibitor ( IC 50 = 0.311 μM), covalently binds to the Sec 46 site of GPX4.
- GC81552OnvontatugCAS: 3037073-85-8Purity: >99.50%
Onvontatug (BAT8006 Antibody) is a humanized monoclonal antibody targeting folate receptor α ( FRα ).
- GC81597Momilactone BCAS: 51415-08-8Purity: >99.00%
Momilactone B is an inhibitor of α-amylase and α-glucosidase, with an IC 50 of 146.85 μg/mL against Aspergillus oryzae α-amylase and an IC 50 of 612.03 μg/mL against Saccharomyces cerevisiae α-glucosidase.
- GC816264-Methoxyestradiol-d 5Purity: >98.00%
4-Methoxyestradiol -d 5 is the deuterium labeled 4-Methoxyestradiol.
- GC81655Poly(A) polymeraseCAS: 9026-30-6Purity: >98.00%
Poly(A) polymerase catalyzes the incorporation of ATP into the RNA 3' end in the form of AMP, that is, adding a polyadenosine tail at the RNA 3' end.
- GC816573'-Fluorothymidine-5'-triphosphate tetrasodiumCAS: 1443116-39-9Purity: >99.50%
3'-Fluorothymidine-5'-triphosphate tetrasodium (3'-FdTTP tetrasodium) is a dTTP analog.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81508 | Unylinker-OH Resin (Substitution:300±25 µmol/g) | - | >98.00% | |
Unylinker-OH Resin (Substitution:300±25 µmol/g) is a macroporous polystyrene resin functionalized with Unylinker active groups with uniform particle size and uniform active groups. | ||||
| GC81509 | DMTr-2'-O-C22-rU-3'-CE-phosphoramidite | 2923115-86-8 | >98.00% | |
DMTr-2'-O-C22-rU-3'-CE-phosphoramidite is an RNA phosphoramidite monomer. | ||||
| GC81512 | dCDK9-202 | - | >98.50% | |
dCDK9-202 is a CDK9 PROTAC degrader with a DC 50 of 3.5 nM. | ||||
| GC81514 | PROTAC SMARCA2 degrader-35 | 3032998-97-0 | >98.00% | |
PROTAC SMARCA2 degrader-35 (Compound 43) is a selective SMARCA2 PROTAC degrader with a DC 50 < 0.1 μM for SMARCA2. | ||||
| GC81521 | 2',3'-ddA(N-Bz) Phosphoramidite | - | >98.00% | |
2',3'-ddA(N-Bz) Phosphoramidite is a modified phosphoramidite monomer that can be used for the synthesis of oligonucleotides. | ||||
| GC81522 | WWZ-11-098 | - | >98.00% | |
WWZ-11-098 is a selective CDK6 PROTAC degrader with DC 50 of 2.6 nM. | ||||
| GC81527 | Sofetabart | 3066905-22-1 | >98.00% | |
Sofetabart (LY-4170156 Antibody) is a humanized IgG1 antibody that specifically targets folate receptor α ( FRα ). | ||||
| GC81528 | (5-Cl)-Exatecan TFA | - | >98.00% | |
(5-Cl)-Exatecan TFA is a derivative of Exatecan and a DNA topoisomerase inhibitor. | ||||
| GC81529 | ZW-191 | - | >98.00% | |
ZW-191 is an antibody-drug conjugate (ADC) targeting folate receptor α (FRα). | ||||
| GC81530 | Elfetabart drozuntecan | 3061153-84-9 | >98.00% | |
Elfetabart drozuntecan (DB-1311; BNT324) is an antibody-drug conjugate ( ADC ) targeting B7H3. | ||||
| GC81531 | PBX-7016 | 3003834-34-9 | >98.00% | |
PBX-7016 is a DNA topoisomerase I inhibitor and DDX5 degrader. | ||||
| GC81543 | GPX4-IN-19 | 3102894-57-2 | >99.00% | |
GPX4-IN-19 is an effective GPX4 inhibitor ( IC 50 = 0.311 μM), covalently binds to the Sec 46 site of GPX4. | ||||
| GC81551 | ZNF281-IN-1 | - | >98.00% | |
ZNF281-IN-1 is a ZNF281 inhibitor. | ||||
| GC81552 | Onvontatug | 3037073-85-8 | >99.50% | |
Onvontatug (BAT8006 Antibody) is a humanized monoclonal antibody targeting folate receptor α ( FRα ). | ||||
| GC81553 | YRDC-IN-1 | 3120494-74-5 | >93.50% | |
YRDC-IN-1 is a blood-brain barrier-permeable YRDC inhibitor. | ||||
| GC81594 | TLSC702 | 748786-57-4 | >95.50% | |
TLSC702 is a human glyoxalase I ( hGLO I ) inhibitor with an IC 50 of 2.0 μM. | ||||
| GC81595 | BCS12 | 329719-71-3 | >99.50% | |
BCS12 is a CAIX inhibitor. | ||||
| GC81597 | Momilactone B | 51415-08-8 | >99.00% | |
Momilactone B is an inhibitor of α-amylase and α-glucosidase, with an IC 50 of 146.85 μg/mL against Aspergillus oryzae α-amylase and an IC 50 of 612.03 μg/mL against Saccharomyces cerevisiae α-glucosidase. | ||||
| GC81618 | Urolithin A- 13 C 6 | - | >99.50% | |
Urolithin A - 13 C 6 is the 13 C-labeled Urolithin A. | ||||
| GC81626 | 4-Methoxyestradiol-d 5 | - | >98.00% | |
4-Methoxyestradiol -d 5 is the deuterium labeled 4-Methoxyestradiol. | ||||
| GC81654 | 2-5A TEA | 72351-33-8 | >98.00% | |
2-5A TEA (2′,5′-ApApA TEA) is a 5'-triphosphorylated (2',5') oligoadenylate. | ||||
| GC81655 | Poly(A) polymerase | 9026-30-6 | >98.00% | |
Poly(A) polymerase catalyzes the incorporation of ATP into the RNA 3' end in the form of AMP, that is, adding a polyadenosine tail at the RNA 3' end. | ||||
| GC81656 | DNA-GAGA | 110138-50-6 | >98.00% | |
DNA-GAGA is a slow substrate for Ricin toxin A-chain (RTA). | ||||
| GC81657 | 3'-Fluorothymidine-5'-triphosphate tetrasodium | 1443116-39-9 | >99.50% | |
3'-Fluorothymidine-5'-triphosphate tetrasodium (3'-FdTTP tetrasodium) is a dTTP analog. | ||||