Veratridine |
Catalog No.GC14730 |
La veratridina (3-Veratroylveracevine) es una neurotoxina vegetal, un bloqueador de los canales de sodio dependientes de voltaje (VGSC).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 71-62-5
Sample solution is provided at 25 µL, 10mM.
Voltage-gated Na+ channel opener; increases intracellular Ca2+ with no effect on the Na+/Ca2+ exchanger. Steroid-derived alkaloid neurotoxin. Increases membrane Na+ permeability and depolarizes excitable tissues.
Reference:
[1]. Purification, solubility and pKa of veratridine.
McKinney et al.
Anal.Biochem., 1986;153:33
[2]. Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine.
Maroto et al.
Eur.J.Pharmacol., 1994;270:331
[3]. Mechanism of the persistant sodium current activator veratridine-evoked Ca2+ elevation: implication for epilepsy.
Fekete et al.
J.Neurochem., 2009;111:745
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