>>Signaling Pathways>> Membrane Transporter/Ion Channel>> Sodium Channel>>Veratridine

Veratridine

Catalog No.GC14730

베라트리딘(3-Veratroylveracevine)은 식물 신경독, 전압 개폐 나트륨 채널(VGSC) 차단제입니다.

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Veratridine Chemical Structure

Cas No.: 71-62-5

Size 가격 재고 수량
10mg
US$193.00
재고 있음
50mg
US$549.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Protocol Chemical Properties Product Documents Related Products

Voltage-gated Na+ channel opener; increases intracellular Ca2+ with no effect on the Na+/Ca2+ exchanger. Steroid-derived alkaloid neurotoxin. Increases membrane Na+ permeability and depolarizes excitable tissues.

Reference:
[1]. Purification, solubility and pKa of veratridine.
      McKinney et al.
     Anal.Biochem., 1986;153:33
[2]. Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+      oscillations induced by veratridine.
     Maroto et al.
     Eur.J.Pharmacol., 1994;270:331
[3]. Mechanism of the persistant sodium current activator veratridine-evoked Ca2+ elevation:      implication for epilepsy.
     Fekete et al.
     J.Neurochem., 2009;111:745

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