Veratridine |
| Katalog-Nr.GC14730 |
Veratridin (3-Veratroylveracevine) ist ein pflanzliches Neurotoxin, ein Blocker der spannungsgesteuerten NatriumkanÄle (VGSCs).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 71-62-5
Sample solution is provided at 25 µL, 10mM.
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Voltage-gated Na+ channel opener; increases intracellular Ca2+ with no effect on the Na+/Ca2+ exchanger. Steroid-derived alkaloid neurotoxin. Increases membrane Na+ permeability and depolarizes excitable tissues.
Reference:
[1]. Purification, solubility and pKa of veratridine.
McKinney et al.
Anal.Biochem., 1986;153:33
[2]. Effects of Ca2+ channel antagonists on chromaffin cell death and cytosolic Ca2+ oscillations induced by veratridine.
Maroto et al.
Eur.J.Pharmacol., 1994;270:331
[3]. Mechanism of the persistant sodium current activator veratridine-evoked Ca2+ elevation: implication for epilepsy.
Fekete et al.
J.Neurochem., 2009;111:745
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