GPCR/G protein
Research Areas
- Neuropeptide FF/AF Receptors(51)
- Neuropeptide S Receptor(3)
- GPBA Receptor(3)
- Trace Amine 1 Receptor(2)
- GPCR protein(1)
- FFAR3(1)
- Formyl Peptide Receptors(11)
- 5-HT Receptor(414)
- Acetylcholine(28)
- Adenosine Deaminase(10)
- Adenosine Receptor(138)
- Adenosine Kinase(5)
- Adiponectin Receptor(3)
- Adrenergic Receptor(431)
- Adrenergic Transporters(5)
- Apelin Receptor(9)
- Angiotensin Receptor(117)
- Bombesin Receptors(23)
- Bradykinin Receptors(29)
- Calcitonin and Related Receptors(10)
- Cannabinoid Receptor(111)
- Calcimimetic Agent(2)
- CaSR(25)
- CCK1 Receptors(7)
- CCK2 Receptors(7)
- CCR(95)
- Chemokine Receptors(23)
- CRF1 Receptors(10)
- CRF2 Receptors(3)
- CXCR(93)
- CysLT1 receptor(1)
- Endothelin Receptor(53)
- EP1 Receptor(2)
- EP4 Receptor(2)
- ERRγ(1)
- ETA Receptors(5)
- ETB Receptors(5)
- Free Fatty Acid Receptors(16)
- Galanin Receptors(11)
- Ghrelin Receptors(11)
- GHSR(20)
- GIP Receptor(5)
- Glucagon Receptor(54)
- Glucocorticoid Receptor(94)
- GLUT1(1)
- Gonadotropin-Releasing Hormone Receptors(3)
- GPCR19(12)
- GPR109A(4)
- GPR119(10)
- GPR120(9)
- GPR35(10)
- GPR44(1)
- GPR55(11)
- Hydroxycarboxylic Acid Receptors(5)
- Leukotriene Receptor(57)
- LPA Receptor(12)
- LPL Receptor(62)
- LTD4 Receptor(1)
- mGluR (123)
- Melanin-concentrating Hormone Receptors(7)
- Melanocortin (MC) Receptors(57)
- Melatonin Receptors(23)
- Motilin Receptor(7)
- MT Receptor(1)
- Non-selective CRF(7)
- Neurotensin Receptors(26)
- NK2 Receptors(7)
- NK3 Receptor(5)
- NOP Receptor(20)
- NPY Receptors(26)
- Orexin(3)
- Orphan 7-TM Receptors(6)
- OX Receptor(52)
- Oxytocin Receptors(22)
- P2Y Receptor(65)
- PACAP Receptors(7)
- PAF Receptors(7)
- Peptide Receptors(14)
- PGD2 Receptor(1)
- Prostaglandin Receptor(174)
- Prostanoid Receptors(25)
- Protease-Activated Receptors(9)
- RGS(2)
- S1P receptor(8)
- Secretin Receptors(1)
- Sensory Neuron-Specific Receptors(1)
- Somatostatin Receptor(43)
- Sigma Receptor(59)
- Vasopressin Receptor(34)
- 17,20-lyase(4)
- Ras(163)
- Urotensin-II Receptor(10)
- VIP Receptors(6)
- EBI2/GPR183(7)
- TSH Receptor(10)
- NK Receptor(1)
- GPR81(1)
- C3aR(1)
- CysLT2 receptor(1)
- S1P receptor inhibitor(22)
- CCKB(1)
- FFAR1 (GPR40)(20)
- GPR84(10)
- Neuromedin U Receptors(2)
- Kisspeptin Receptor(6)
- CRFR(27)
- RGS Protein(5)
- Urotensin Receptor(7)
- Cholecystokinin Receptor(28)
- GPR139(4)
- mAChR(191)
- MCHR1 (GPR24)(16)
- Neurokinin Receptor(76)
- cGMP(27)
- GRK(3)
- GPR88(1)
- Amylin Receptor(3)
- Arrestin(8)
- Mas-related G-protein-coupled Receptor (MRGPR)(6)
- GCGR(7)
- GLP Receptor(16)
- Succinate Receptor 1(1)
- PTHR(2)
- Protease Activated Receptor (PAR)(6)
- Free Fatty Acid Receptor(5)
- Formyl Peptide Receptor (FPR)(3)
- Hydroxycarboxylic Acid Receptor (HCAR)(2)
- RXFP Receptor(2)
- Adhesion G Protein-coupled Receptors (AGPCRs)(1)
- Taste Receptor(1)
- GPR52(1)
Products Related to GPCR/G protein(3538)
- GC79667AGFAGDDAPRCAS: 330204-04-1Purity: >98.00%
AGFAGDDAPR is a bioactive peptide that is a competitive and orally effective inhibitor of dipeptidyl peptidase-IV ( DPP-IV ).
- GC79721Substance P, free acid TFAPurity: >98.00%
Substance P, Free Acid TFA is a native substance P analog, but shows no biological activity of substance P [1] .
- GC79723AlofropodectCAS: 1829530-11-1Purity: >98%
Alofropodect is an orally active, blood-brain barrier permeable phosphodiesterase 10A ( PDE10A ) inhibitor with IC 50 values of 1 nM (Reference 1) and 35 nM (Reference 2).
- GC79779N-Desmethyl xanomelineCAS: 131986-96-4Purity: >98%
N-Desmethyl xanomeline is a pharmacologically active metabolite of Xanomeline.
- GC79780SERT/5-HT-IN-1CAS: 3120534-54-2Purity: >99.00%
SERT/5-HT-IN-1 (compound D17) is an orally active and potent dual target inhibitor of SERT/5-HT3A ( SERT IC 50 = 1.5 nM, NET IC 50 = 49 nM, DAT IC 50 = 91 nM, 5-HT3A K i = 12 nM).
- GC79808SAR113945 monopotassiumCAS: 899418-65-6Purity: >98%
SAR113945 monopotassium is a highly selective IKK-β inhibitor with an IC 50 value of 0.4 nM.
- GC804048-(p-Sulfophenyl)theophyllineCAS: 80206-91-3Purity: >98.00%
8-(p-Sulfophenyl)theophylline (8-SPT) (compound 2) is an adenosine A2B receptor antagonist, with a K i of 1330 nM for A2B human recombinant [1] .
- GC80405Tricosanoic acid-d 3CAS: 2732915-45-4Purity: >98%
Tricosanoic acid -d 3 is the deuterium labeled Tricosanoic acid.
- GC80406(±)-Clopidogrel-d 4CAS: 1219274-95-9Purity: >99.50%
(±)-Clopidogrel-d 4 ((±)-Clopidogrelum-d 4 ) is the deuterium labeled (±)-Clopidogrel.
- GC80407Semaglutide-d 8 tetraTFAPurity: >99.50%
Semaglutide -d 8 tetraTFA is the deuterium labeled Semaglutide.
- GC80473Pregnenolone-d 6Purity: >98%
Pregnenolone -d 6 (3β-Hydroxy-5-pregnen-20-one-d 6 ) is the deuterium labeled Pregnenolone [1] . Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones.
- GC80835Didesmethyl cariprazine-d 8CAS: 1308279-08-4Purity: >99.00%
Didesmethyl cariprazine -d 8 is the deuterium labeled Didesmethyl cariprazine.
- GC80836rac-LevonordefrinCAS: 6539-57-7Purity: >98.00%
Rac-Levonordefrin (rac-Cobefrin; rac-α-Methylnoradrenaline; rac-Nordefrin) is the racemic form of Levonordefrin.
- GC80837Desmethyl cariprazine-d 8CAS: 1308278-85-4Purity: >99.50%
Desmethyl cariprazine -d 8 is the deuterium labeled Desmethyl cariprazine.
- GC80838Orexin B, human- 13 C 18 , 15 N 3 TFAPurity: >96.50%
Orexin B, human - 13 C 18, 15 N 3 (Human orexin B- 13 C 18, 15 N 3 ) TFA is the 13 C- and 15 N-labeled Orexin B, human.
- GC80839Orexin A- 13 C 18 , 15 N 3 (human, rat, mouse) TFAPurity: >98.50%
Orexin A- 13 C 18, 15 N 3 (human, rat, mouse) ((Hypocretin-1- 13 C 18, 15 N 3 (human, rat, mouse)) TFA is the 13 C- and 15 N-labeled Orexin A (human, rat, mouse).
- GC80840Arecoline-d 5 hydrobromideCAS: 131448-18-5Purity: >98.00%
Arecoline-d 5 hydrobromide is the deuterium labeled Arecoline hydrobromide.
- GC80861Teriparatide-d 10Purity: >98%
Teriparatide -d 10 (Human parathyroid hormone-(1-34)-d 10 ) is the deuterium labeled Teriparatide.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC79507 | PSB-12054 | 1407632-07-8 | >98.50% | |
PSB-12054 is a P2X4 receptor antagonist with IC 50 values of 0.19 μM, 2.10 μM and 1.77 μM against human, rat and mouse receptors, respectively, and exhibits selectivity over other human P2X receptor subtypes. | ||||
| GC79667 | AGFAGDDAPR | 330204-04-1 | >98.00% | |
AGFAGDDAPR is a bioactive peptide that is a competitive and orally effective inhibitor of dipeptidyl peptidase-IV ( DPP-IV ). | ||||
| GC79668 | RES-701-3 peptide TFA | - | >98.00% | |
RES-701-3 peptide TFA is a class II lasso peptide. | ||||
| GC79675 | FTO-IN-17 | 1434867-98-7 | >98% | |
FTO-IN-17 is an orally active and brain-penetrant FTO (m 6 A RNA demethylase) inhibitor with an IC 50 of 1.1 μM. | ||||
| GC79707 | ST1072 | 1402703-50-7 | >98% | |
ST1072 is an inhibitor of CerS4 and CerS6. | ||||
| GC79721 | Substance P, free acid TFA | - | >98.00% | |
Substance P, Free Acid TFA is a native substance P analog, but shows no biological activity of substance P [1] . | ||||
| GC79722 | Escholtzine perchlorate | 77790-29-5 | >98.00% | |
Escholtzine perchlorate is an Alkaloid. | ||||
| GC79723 | Alofropodect | 1829530-11-1 | >98% | |
Alofropodect is an orally active, blood-brain barrier permeable phosphodiesterase 10A ( PDE10A ) inhibitor with IC 50 values of 1 nM (Reference 1) and 35 nM (Reference 2). | ||||
| GC79779 | N-Desmethyl xanomeline | 131986-96-4 | >98% | |
N-Desmethyl xanomeline is a pharmacologically active metabolite of Xanomeline. | ||||
| GC79780 | SERT/5-HT-IN-1 | 3120534-54-2 | >99.00% | |
SERT/5-HT-IN-1 (compound D17) is an orally active and potent dual target inhibitor of SERT/5-HT3A ( SERT IC 50 = 1.5 nM, NET IC 50 = 49 nM, DAT IC 50 = 91 nM, 5-HT3A K i = 12 nM). | ||||
| GC79808 | SAR113945 monopotassium | 899418-65-6 | >98% | |
SAR113945 monopotassium is a highly selective IKK-β inhibitor with an IC 50 value of 0.4 nM. | ||||
| GC80404 | 8-(p-Sulfophenyl)theophylline | 80206-91-3 | >98.00% | |
8-(p-Sulfophenyl)theophylline (8-SPT) (compound 2) is an adenosine A2B receptor antagonist, with a K i of 1330 nM for A2B human recombinant [1] . | ||||
| GC80405 | Tricosanoic acid-d 3 | 2732915-45-4 | >98% | |
Tricosanoic acid -d 3 is the deuterium labeled Tricosanoic acid. | ||||
| GC80406 | (±)-Clopidogrel-d 4 | 1219274-95-9 | >99.50% | |
(±)-Clopidogrel-d 4 ((±)-Clopidogrelum-d 4 ) is the deuterium labeled (±)-Clopidogrel. | ||||
| GC80407 | Semaglutide-d 8 tetraTFA | - | >99.50% | |
Semaglutide -d 8 tetraTFA is the deuterium labeled Semaglutide. | ||||
| GC80414 | (S)-IDOR-1117-2520 | - | >99.00% | |
(S)-IDOR-1117-2520 is the S-isomer of IDOR-1117-2520. | ||||
| GC80473 | Pregnenolone-d 6 | - | >98% | |
Pregnenolone -d 6 (3β-Hydroxy-5-pregnen-20-one-d 6 ) is the deuterium labeled Pregnenolone [1] . Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. | ||||
| GC80835 | Didesmethyl cariprazine-d 8 | 1308279-08-4 | >99.00% | |
Didesmethyl cariprazine -d 8 is the deuterium labeled Didesmethyl cariprazine. | ||||
| GC80836 | rac-Levonordefrin | 6539-57-7 | >98.00% | |
Rac-Levonordefrin (rac-Cobefrin; rac-α-Methylnoradrenaline; rac-Nordefrin) is the racemic form of Levonordefrin. | ||||
| GC80837 | Desmethyl cariprazine-d 8 | 1308278-85-4 | >99.50% | |
Desmethyl cariprazine -d 8 is the deuterium labeled Desmethyl cariprazine. | ||||
| GC80838 | Orexin B, human- 13 C 18 , 15 N 3 TFA | - | >96.50% | |
Orexin B, human - 13 C 18, 15 N 3 (Human orexin B- 13 C 18, 15 N 3 ) TFA is the 13 C- and 15 N-labeled Orexin B, human. | ||||
| GC80839 | Orexin A- 13 C 18 , 15 N 3 (human, rat, mouse) TFA | - | >98.50% | |
Orexin A- 13 C 18, 15 N 3 (human, rat, mouse) ((Hypocretin-1- 13 C 18, 15 N 3 (human, rat, mouse)) TFA is the 13 C- and 15 N-labeled Orexin A (human, rat, mouse). | ||||
| GC80840 | Arecoline-d 5 hydrobromide | 131448-18-5 | >98.00% | |
Arecoline-d 5 hydrobromide is the deuterium labeled Arecoline hydrobromide. | ||||
| GC80861 | Teriparatide-d 10 | - | >98% | |
Teriparatide -d 10 (Human parathyroid hormone-(1-34)-d 10 ) is the deuterium labeled Teriparatide. | ||||