Metabolism
- Sterol Biosynthesis(26)
- PPAR(216)
- 5-alpha Reductase(9)
- 5-Lipoxygenase(11)
- Adenosine Deaminase(8)
- Aminopeptidase(10)
- C14ɑ demethylase(2)
- Carbonic Anhydrase(63)
- CETP(13)
- Cholesterol absorption(1)
- CPT1(3)
- CYP3A/CYP450(26)
- Dehydrogenase(139)
- DHFR(11)
- DGAT(13)
- Dopamine β-hydroxylase(14)
- Enolase(11)
- FAAH(40)
- Factor Xa(49)
- Ferroptosis(200)
- Folate Analogue(3)
- Glucokinase(17)
- HLE(1)
- HMG-CoA Reductase(39)
- HSP(77)
- IDO(52)
- KRAS-PDEδ(4)
- MAO(9)
- Metabolic Enzymes(0)
- Neuronal Metabolism(8)
- Oxidative Phosphorylation(17)
- P450(146)
- PDE(254)
- Phospholipase(117)
- Procollagen C Proteinase(2)
- Saccharometabolism(1)
- SCD(19)
- SGLT(31)
- TPH(6)
- Transferase(183)
- Energy Metabolism(0)
- Inorganic Ions(0)
- ALP(1)
- Carbohydrates(18)
- Uric Acid(0)
- Muscle Metabolism(0)
- MDA(0)
- MPO(0)
- Transaminase(20)
- Glutathione Reductase(0)
- Thioredoxin Reductase(0)
- Catalase(8)
- monooxygenase(1)
- PKM2(1)
- aldehyde dehydrogenase(1)
- Squalene synthase(1)
- Hydrolase(47)
- ornithine decarboxylase(1)
- Amino acid metabolism(3)
- phosphatases(98)
- Pyruvate kinase(9)
- Others(4)
- MGL(1)
- Galactosidase(6)
- 12-Lipoxygenase(1)
- Fatty Acid Synthase (FASN)(9)
- Dihydroorotate Dehydrogenase(12)
- Bile Acids & Microbiome(94)
- Bone Growth & Remodeling(35)
- Carbohydrate Metabolism(126)
- Cofactors & Vitamins(64)
- Dyslipidemias(73)
- Inborn Errors of Metabolism(80)
- Metabolic Syndrome(16)
- Necroptosis(10)
- Necrosis(15)
- Nutrient Sensing(12)
- Phosphodiesterase(27)
- Reproductive Biology(126)
- Thermogenesis(6)
- Prolyl Hydroxylation Enzymes(1)
- Biliary System(4)
- Metabolic Disease(4)
- Fat Mass and Obesity-associated Protein (FTO)(2)
- SHIP(1)
منتجات لـ نبسب؛ Metabolism
- القط. رقم اسم المنتج بيانات
- GC18575 2-hydroxy Tricosanoic Acid methyl ester 2-hydroxy Tricosanoic acid methyl ester is a hydroxylated fatty acid methyl ester that has been found in ripe and unripe strawberry homogenates, Pseudosuberites and S.
- GC49840 2-Methylbutyrylglycine A metabolite of isoleucine
- GC48617 2-Methylhexacosane An insect pheromone
- GC52170 2-Nitroamino-2-imidazoline
- GC42189 2-oxo Clopidogrel 2-oxo Clopidogrel is an intermediary metabolite of clopidogrel.
- GC12262 2-Phenyl-2-(1-piperidinyl)propane 2-Phenyl-2- (1-piperidinyl) البروبان هو مثبط انتقائي وقابل للانعكاس CYP2B6 بشري مع IC 50 من 5.1 ميكرومتر و Ki 5.6
- GC42193 2-Thenoyltrifluoroacetone 2-Thenoyltrifluoroacetone هو عامل مخلب
- GC52083 21-Deoxycortisone A corticosteroid metabolite of 11-keto progesterone
- GC40968 21-hydroxy Eplerenone 21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone.
- GC18270 22(S)-hydroxy Cholesterol A synthetic oxysterol and LXR modulator
-
GC41614
24-dehydro Cholesterol
24-ديهيدروكولسترول هو جزيء مشابه للكولسترول.
- GC46243 24-dehydro Cholesterol-d6 An internal standard for the quantification of 24-dehydro cholesterol
- GC49365 25-Desacetyl Rifampicin A major active metabolite of rifampicin
- GC18490 2α-Mannobiose 2α-Mannobiose is a disaccharide composed of two mannose molecules linked by a 1-2 glycosidic bond.
- GC49658 3β-Cholic Acid A bile acid
- GC46068 3β-OH-7-Oxocholenic Acid A bile acid
- GC33059 3α-Aminocholestane 3&alpha ؛ -Aminocholestane هو مجال انتقائي SH2 يحتوي على مثبط inositol-5′-phosphatase 1 (SHIP1) مع IC50 من حوالي 2.5 ميكرومتر.
- GC41480 3'-hydroxy Lidocaine 3'-hydroxy Lidocaine is an active metabolite of lidocaine formed by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP3A4.
- GC42312 3'-Sialyllactose (sodium salt) 3'-Sialyllactose consists of the monosaccharide N-acetylneuraminic acid linked to the galactosyl subunit of lactose at the 3 position.
- GC52109 3,3′-Dipropylthiadicarbocyanine (iodide) 3،3′ ؛ -Dipropylthiadicarbocyanine (يوديد) هو مسبار فلوري يستخدم غالبًا كصبغة تتبع لتقييم إمكانات غشاء الميتوكوندريا.
- GC46030 3,3'-((2-Chlorophenyl)methylene)bis(4-hydroxy-2H-chromen-2-one) An ENPP1 inhibitor
- GC42204 3,4,6-Tri-O-benzyl-β-D-Mannopyranose 1,2-(methyl orthoacetate) 3,4,6-Tri-O-benzyl-β-D-mannopyranose 1,2-(methyl orthoacetate) is a synthetic intermediate used in glycosylation reactions.
- GC12624 3,4-DAA synthetic derivative of the tryptophan metabolite anthranilic acid
- GC49427 3,5-Diiodo-L-thyronine 3،5-ديودو- L- ثيرونين هو مستقلب داخلي.
- GC18205 3,5-Diiodothyroacetic Acid 3,5-Diiodothyroacetic acid (diac) is the acetic acid variant of thyroxine.
- GC49169 3,8’-Biapigenin 3،8& رسقوو ؛ -بابيجينين هو بيفلافون في Hypericum perforatum L.
- GC52324 3-(3-Hydroxyphenyl)propionic Acid sulfate A metabolite of certain phenols and glycosides
- GC42198 3-(4-Chlorophenyl)-4-hydroxybutyric Acid (sodium salt) An inactive metabolite of baclofen
- GC14282 3-acetyl-11-keto-β-Boswellic Acid 3-acetyl-11-keto-β؛ -Boswellic Acid (Acetyl-11-keto-β؛ -boswellic acid) هو مركب ثلاثي التيربينويد نشط من مستخلص Boswellia serrate ومنشط Nrf2 جديد.
- GC46583 3-Amino-2,6-Piperidinedione An active metabolite of (±)-thalidomide
- GC52129 3-Amino-5-hydroxybenzoic Acid
- GC10554 3-Cyano-7-ethoxycoumarin 3-Cyano-7-ethoxycoumarin عبارة عن ركيزة فلورية من السيتوكروم P-450 تولد منتجًا فلوريًا أزرق عند انقسام الإنزيم الهدف: السيتوكروم P4503-Cyano-7-ethoxycoumarin عبارة عن مسبار فلوري مفيد في دراسات dealkylase الميكروسومية
- GC14713 3-Deazaadenosine 3-Deazaadenosine مثبط لـ S-adenosylhomocysteine hydrolase ، مع Ki 3.9 ميكرومتر ؛ 3-ديازادينوسين له نشاط مضاد للالتهابات ومضاد للتكاثر ومضاد لفيروس نقص المناعة البشرية
-
GC42261
3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid
Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition, as well as the formation and progression of tumors.
- GC49180 3-epi-25-hydroxy Vitamin D3 The C-3 epimer of 25-hydroxy vitamin D3
- GC18462 3-Formylsalicylic Acid 3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM; Ki = 120 nM), the enzyme that converts estrone sulfate to estrone.
- GC41632 3-hydroxy Carbofuran 3-hydroxy Carbofuran is an active metabolite of carbofuran, which is an insecticide that inhibits acetylcholinesterase in mammals and insects.
- GC42274 3-hydroxy Darifenacin 3-hydroxy Darifenacin is a metabolite of darifenacin.
- GC42275 3-hydroxy Desloratidine 3-hydroxy Desloratidine is a major metabolite of desloratadine , a tricyclic antagonist of the histamine H1 receptor.
- GC41565 3-hydroxy Medetomidine 3-hydroxy Medetomidine is a metabolite of the α2-adrenergic receptor agonist medetomidine.
- GC42289 3-hydroxy Tridecanoic Acid methyl ester 3-hydroxy Tridecanoic acid methyl ester is a hydroxylated fatty acid methyl ester and major fatty acid component of A.
- GC42292 3-Hydroxypropionic Acid (sodium salt) 3-Hydroxypropionic acid is a building block in the synthesis of a variety of compounds with industrial applications, including acrylic acid, acrylamide, and 1,3-propanediol.
- GC48457 3-keto Fusidic Acid An active metabolite of fusidic acid
- GC49149 3-Methylglutaconic Acid A branched-chain organic acid
-
GC65595
3-Nitrocoumarin
3-نيتروكومارين (3-NC) هو مثبط قوي وانتقائي لفسفوليباز سي - جاما (PLC-γ).
- GC17394 3-Nitropropionic acid 3-حمض النيتروبروبيونيك (β ؛ - حمض النيتروبروبيونيك) هو مثبط لا رجعة فيه لنزعة هيدروجين السكسينات.
- GC42307 3-O-methyl-L-DOPA (hydrate) 3-O-methyl-L-DOPA is a metabolite of L-DOPA, produced by the activity of catechol O-methyltransferase.
- GC42308 3-O-methyl-N-acetyl-D-Glucosamine 3-O-Methyl-N-acetyl-D-glucosamine هو مثبط قوي لـ N-acetylglucosamine kinase
- GC60024 3-O-Methylquercetin 3-O-Methylquercetin (3-MQ) ، مكون رئيسي من Rhamnus nakaharai ، يثبط cAMP و cGMP-phosphodiesterase (PDE) من القصبة الهوائية لخنزير غينيا
- GC40692 3-Propylxanthine يعمل 3-Propylxanthine كمضاد لمستقبل A2B انتقائي وتنافسي مع Ki من μ ؛ M.
- GC12289 3-Thiatetradecanoic Acid activator of PPAR
-
GC52149
306-O12B
شحمية مؤيونة كاتيونية
- GC46678 4β-hydroxy Cholesterol-d7 An internal standard for the quantification of 4β-hydroxy cholesterol
- GC49367 4’-hydroxy Atomoxetine Glucuronide (hydrate) A metabolite of atomoxetine
- GC49252 4’-hydroxy Trazodone A metabolite of trazodone
- GC18527 4'-hydroxy Flurbiprofen A major active metabolite of flurbiprofen
- GC33071 4'-Methylchrysoeriol 4'-Methylchrysoeriol هو مثبط قوي لإنزيمات السيتوكروم P450 ، مع IC50 من 19 نانومتر للإنسان المعتمد على P450 1B1 EROD
- GC41582 4(Z),7(Z)-Decadienoic Acid 4(Z),7(Z)-Decadienoic acid is a polyunsaturated fatty acid (PUFA).
- GC42326 4,6-O-Benzylidene-D-glucose 4,6-O-Benzylidene-D-glucose is a useful intermediate for the synthesis of carbohydrates.
- GC17159 4-(n-nonyl) Benzeneboronic Acid 4- (n-nonyl) Benzeneboronic Acid (المركب 13) هو مثبط ثنائي فعال FAAH و MAGL بقيم IC50 تبلغ 9.1 نانومتر و 7.9 μ ؛ M ، على التوالي.
- GC65517 4-(Trifluoromethyl)umbelliferone 4- (Trifluoromethyl) umbelliferone هو ركيزة مسبار الفلورسنت لأنزيمات السيتوكروم P450 الكبدية للفئران
- GC49337 4-Acetamidobenzenesulfonamide A metabolite of asulam and sulfanilamide
- GC46069 4-Amino-5-(bromomethyl)-2-methylpyrimidine (hydrobromide) 4-أمينو -5 (بروموميثيل) -2-ميثيل بيريميدين (هيدروبروميد) هو مثبط كيناز مستقبلات مقترنة ببروتين G (GRK).
- GC42337 4-Aminobenzoic Acid (sodium salt) 4-Aminobenzoic acid, commonly known as PABA, is an intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi.
- GC49494 4-Aminobenzylphosphonic Acid An alkaline phosphatase inhibitor
- GC18194 4-Epidoxycycline 4-Epidoxycycline is the 4-epimer hepatic metabolite of the antibiotic doxycycline .
- GC18858 4-hydroxy Alternariol 4-hydroxy Alternariol is a metabolite of the mycotoxin alternariol formed through cytochrome P450 (CYP450) metabolism.
- GC42405 4-hydroxy Atorvastatin (calcium salt) 4-hydroxy Atorvastatin is a metabolite of atorvastatin, an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
-
GC18425
4-hydroxy Atorvastatin lactone
4-hydroxy Atorvastatin lactone is a metabolite of atorvastatin , an HMG-CoA reductase inhibitor present in formulations that have been used to treat hypercholesterolemia and certain dyslipidemias.
- GC49575 4-hydroxy Omeprazole sulfide A metabolite of omeprazole
- GC40879 4-hydroxy Solifenacin N-oxide 4-hydroxy Solifenacin N-oxide is an N-oxide form of 4-hydroxy solifenacin, the major metabolite of solifenacin .
- GC42415 4-hydroxy Valsartan 4-hydroxy Valsartan is a major metabolite of the angiotensin II type 1 (AT1) receptor antagonist valsartan.
-
GC18417
4-hydroxy Xylazine
4-هيدروكسي كزيلات هو متابوليت للكزيلات.
- GC60519 4-Hydroxyderricin 4-Hydroxyderricin ، المكونات النشطة الرئيسية لـ Angelica keiskei Koidzumi ، هو مثبط MAO-B انتقائي قوي (مثبطات مونوامين أوكسيديز) مع IC50 من 3.43 ميكرومتر
- GC42434 4-methyl-2-Oxovalerate (sodium salt) 4-methyl-2-Oxovalerate is an immediate precursor and metabolite of L-leucine.
- GC42445 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) 4-Methylumbelliferyl β؛ -D-Galactopyranoside-6-sulfate (ملح الصوديوم) عبارة عن صبغة فلورية.
- GC42446 4-Methylumbelliferyl β-D-N,N'-diacetylchitobioside 4-Methylumbelliferyl β-D-N,N'-diacetylchitobioside (4-μU-(GlcNAc)2) is a fluorogenic substrate for chitinases and chitobiosidases.
- GC42442 4-Methylumbelliferyl 2-sulfamino-2-deoxy-α-D-Glucopyranoside (sodium salt) 4-Methylumbelliferyl 2-sulfamino-2-deoxy-α ؛ -D-Glucopyranoside (ملح الصوديوم) عبارة عن ركيزة فلورية من سلفاميد الهيبارين ، يتم نزع الكبريت منها إلى 4-MU-α ؛ -GlcNH2.
- GC40510 4-Methylumbelliferyl-α-D-Galactopyranoside 4-Methylumbelliferyl-α ؛ -D-Galactopyranoside (4MU-α ؛ -Gal) ، ركيزة لـ α ؛ -Galactosidase A (GLA) ، هو ركيزة زرقاء مؤيدة للفلوروجينيك.
- GC42449 4-Methylumbelliferyl-α-L-Iduronide (free acid) 4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate.
- GC49114 4-Methylumbelliferyl-β-D-Galactoside 4-Methylumbelliferyl-β ؛ -D-Galactoside عبارة عن ركيزة فلورية لـ β ؛ -Galactosidase الذي ينتج عند انشقاقه مادة فلورية زرقاء قابلة للذوبان في الماء يمكن اكتشافها باستخدام مقياس التألق أو مقياس التألق.
-
GC42452
4-Methylumbelliferyl-β-D-N,N',N''-Triacetylchitotrioside
4-ميثيل أومبيليفيريل - β-D-N، N'، N''-ترااسيتيلكيتوترايوزايد هو مادة فعالة تستخدم كمحفز للكشف عن الكيتنازات والشيتوترايسوداز.
- GC11870 4-Methylumbelliferyl-β-D-Glucopyranoside 4-Methylumbelliferyl-β؛ -D-Glucopyranoside ، β ؛ -D-glucoside ، عبارة عن ركيزة فلوروجينية لـ β ؛ -جلوكوزيداز ، يستخدم لفحص β ؛ -نشاط الجلوكوزيداز.
- GC52117 4-Nitrophenyl α-D-Glucopyranoside A colorimetric α-glucosidase substrate
- GC42462 4-Nitrophenyl β-D-Cellotrioside 4-Nitrophenyl β-D-cellotrioside is a chromogenic substrate for endoglucanases and cellobiohydrolases.
- GC18209 4-Nitrophenyl β-D-Cellotetraoside 4-Nitrophenyl β-D-cellotetraoside is small molecule cellulose mimic that consists of a tetramer of D-glucose units joined by β-1-4-glycosidic bonds.
- GC42463 4-Nitrophenyl-N-acetyl-α-D-galactosaminide N-acetyl-D-galactosaminidase catalyzes the cleavage of N-acetylglucosamine (GlcNAc), the monomeric unit of the polymer chitin.
- GC45841 4-Nitrophenyl-N-acetyl-β-D-glucosaminide A chromogenic substrate for N-acetyl-β-glucosaminidase
- GC35143 4-O-Methyl honokiol 4-O-Methyl honokiol هو نيوليجنان طبيعي معزول من Magnolia officinalis ، يعمل كمحفز لـ PPARγ ، ويمنع نشاط NF-B ، ويستخدم في أبحاث السرطان والالتهابات
- GC49127 4-oxo Cyclophosphamide An inactive metabolite of cyclophosphamide
- GC41530 4-oxo Docosahexaenoic Acid 4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity.
- GC49244 4-oxo Isotretinoin An active metabolite of isotretinoin
- GC11731 4-phenyl-1,2,3-Thiadiazole selective inhibitor of certain CYP450 enzymes (CYP2B4, CYP2E1)
- GC11758 4-phenyl-5-methyl-1,2,3-Thiadiazole CYP2B4 and CYP2E1 inhibitor
- GC10762 4β-hydroxy Cholesterol An endogenous marker for CYP3A4/5 activity
- GC48843 5α-Androst-16-en-3α-ol A pheromone with diverse biological activities
- GC49542 5α-Androstan-3β-ol A steroidal androgen
- GC49862 5α-Cholanic Acid-3,6-dione A secondary bile acid
- GC41399 5α-dihydro Levonorgestrel 5α-dihydro Levonorgestrel is a metabolite of the synthetic progestin levonorgestrel.
- GC40693 5α-hydroxy-6-keto Cholesterol 5α ؛ -هيدروكسي -6-كيتو الكوليسترول هو المستقلب الرئيسي لـ β ؛ -بوكسيد (5α ؛ ، 6β ؛ -بوكسيكوليسترول) أثناء التعرض المباشر للخلايا الظهارية البشرية السليمة المزروعة (16-HBE) للأوزون.