Cell Cycle/Checkpoint
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.
Research Areas
- ATM/ATR(28)
- Aurora Kinase(35)
- Cdc42(4)
- Cdc7(3)
- Chk(13)
- c-Myc(51)
- CRM1(10)
- Cyclin-Dependent Kinases(70)
- E1 enzyme(1)
- G-quadruplex(16)
- Haspin(6)
- HMTase(1)
- Kinesin(32)
- Ksp(4)
- Microtubule/Tubulin(300)
- Mps1(17)
- Mitotic(7)
- RAD51(13)
- ROCK(76)
- Rho(13)
- PERK(21)
- PLK(51)
- PTEN(7)
- Wee1(15)
- PAK(29)
- Arp2/3 Complex(10)
- Dynamin(18)
- ECM & Adhesion Molecules(53)
- Cholesterol Metabolism(10)
- Endomembrane System & Vesicular Trafficking(34)
- G1(50)
- G2/M(35)
- G2/S(16)
- Genotoxic Stress(22)
- Inositol Phosphates(65)
- Proteolysis(179)
- Cytoskeleton & Motor Proteins(71)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(2)
- MARK(4)
- NEKs(9)
- ATF6(2)
- ClpP(6)
- Disulfidptosis(1)
- HMG Family(1)
- PDI(1)
- SWI/SNF Complex(7)
- VISTA(4)
- HOXA(1)
Products Related to Cell Cycle/Checkpoint(1536)
- GC49015Phenethyl isothiocyanateCAS: 2257-09-2Purity: >99.00%
An isothiocyanate with anticancer activity
- GC49024Palmitic Acid MaxSpec® StandardCAS: 57-10-3Purity: >95.00%
A quantitative analytical standard guaranteed to meet MaxSpec ® identity, purity, stability, and concentration specifications
- GC49042Benastatin ACAS: 138968-85-1Purity: >90.00%
A bacterial metabolite with diverse biological activities
- GC49072TribenosideCAS: 10310-32-4Purity: >95.00%
Tribenosid ist ein vasoprotektives Mittel, das fÜr die Erforschung von HÄmorrhoiden verwendet werden kann.
- GC49077Podophyllotoxin-d6Purity: >99.00%
An internal standard for the quantification of podophyllotoxin and picropodophyllotoxin
- GC49093Safflower RedCAS: 36338-96-2
Safflower red is an active substance extracted from the flowers of the safflower plant ( Carthamus tinctorius ).
- GC49108Racecadotril-d5CAS: 1246815-11-1Purity: >99.00%
An internal standard for the quantification of racecadotril
- GC49128Phenylbutazone-d9CAS: 1189479-75-1Purity: >99.00%
An internal standard for the quantification of phenylbutazone
- GC49142IsorhoifolinCAS: 552-57-8Purity: >98.00%
Isorhoifolin ist ein Flavonoidglykosid aus Periploca nigrescens-BlÄttern.
- GC49204Nefazodone-d6 (hydrochloride)CAS: 1330236-06-0Purity: >99.00%
An internal standard for the quantification of nefazodone
- GC49205L-Leu-AMC (hydrochloride)CAS: 62480-44-8Purity: >98.00%
L-Leucin-7-amido-4-methylcumarin (Leu-AMC)-Hydrochlorid ist ein hellblaues fluorogenes Peptidylsubstrat fÜr LAP3 (Leucin-Aminopeptidase).
- GC49293Dichlorvos-d6CAS: 203645-53-8Purity: >99.00%
An internal standard for the quantification of dichlorvos
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49014 | Palmitoyl Tetrapeptide-7 (acetate) | - | >98.00% | |
A cosmeceutical peptide | ||||
| GC49015 | Phenethyl isothiocyanate | 2257-09-2 | >99.00% | |
An isothiocyanate with anticancer activity | ||||
| GC49024 | Palmitic Acid MaxSpec® Standard | 57-10-3 | >95.00% | |
A quantitative analytical standard guaranteed to meet MaxSpec ® identity, purity, stability, and concentration specifications | ||||
| GC49042 | Benastatin A | 138968-85-1 | >90.00% | |
A bacterial metabolite with diverse biological activities | ||||
| GC49065 | Metacetamol | 621-42-1 | >98.00% | |
A derivative of acetaminophen | ||||
| GC49072 | Tribenoside | 10310-32-4 | >95.00% | |
Tribenosid ist ein vasoprotektives Mittel, das fÜr die Erforschung von HÄmorrhoiden verwendet werden kann. | ||||
| GC49077 | Podophyllotoxin-d6 | - | >99.00% | |
An internal standard for the quantification of podophyllotoxin and picropodophyllotoxin | ||||
| GC49089 | FR900359 | 107530-18-7 | - | |
FR900359 ist ein Inhibitorder G-Proteine Gα q , Gα 11 , and Gα 14 with IC 50 values of 13.18, 10.47 bzw. 10nM und wird aus den Blättern der Zierpflanze Ardisia crenata isoliert. | ||||
| GC49093 | Safflower Red | 36338-96-2 | - | |
Safflower red is an active substance extracted from the flowers of the safflower plant ( Carthamus tinctorius ). | ||||
| GC49108 | Racecadotril-d5 | 1246815-11-1 | >99.00% | |
An internal standard for the quantification of racecadotril | ||||
| GC49124 | EN219 | 380351-29-1 | >95.00% | |
EN219 ist ein mÄßig selektiver synthetischer kovalenter Ligand gegen ein N-terminales Cystein (C8) von RNF114 mit einem IC50 von 470 nM. EN219 hemmt die RNF114-vermittelte Autoubiquitinierung und p21-Ubiquitinierung. | ||||
| GC49128 | Phenylbutazone-d9 | 1189479-75-1 | >99.00% | |
An internal standard for the quantification of phenylbutazone | ||||
| GC49142 | Isorhoifolin | 552-57-8 | >98.00% | |
Isorhoifolin ist ein Flavonoidglykosid aus Periploca nigrescens-BlÄttern. | ||||
| GC49145 | Z-FR-AMC (trifluoroacetate salt) | - | >98.00% | |
A fluorogenic substrate for cathepsin L | ||||
| GC49163 | N’-Nitrosonornicotine | 80508-23-2 | >98.00% | |
An N-nitrosamine and a carcinogen | ||||
| GC49186 | O-Demethyl Apremilast | 1384441-38-6 | >95.00% | |
An active metabolite of apremilast | ||||
| GC49204 | Nefazodone-d6 (hydrochloride) | 1330236-06-0 | >99.00% | |
An internal standard for the quantification of nefazodone | ||||
| GC49205 | L-Leu-AMC (hydrochloride) | 62480-44-8 | >98.00% | |
L-Leucin-7-amido-4-methylcumarin (Leu-AMC)-Hydrochlorid ist ein hellblaues fluorogenes Peptidylsubstrat fÜr LAP3 (Leucin-Aminopeptidase). | ||||
| GC49244 | 4-oxo Isotretinoin | 71748-58-8 | >98.00% | |
An active metabolite of isotretinoin | ||||
| GC49280 | GSK579289A | 929095-23-8 | >98.00% | |
A Plk1 inhibitor | ||||
| GC49293 | Dichlorvos-d6 | 203645-53-8 | >99.00% | |
An internal standard for the quantification of dichlorvos | ||||
| GC49305 | H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt) | - | >95.00% | |
An RGD-containing tetrapeptide | ||||
| GC49322 | GGACK (hydrochloride) | - | >95.00% | |
A uPA and factor Xa inhibitor | ||||
| GC49334 | Chroman 1 (hydrochloride hydrate) | - | >98.00% | |
A ROCK2 inhibitor | ||||