Cell Cycle/Checkpoint
Cell Cycle
Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.
Research Areas
- ATM/ATR(28)
- Aurora Kinase(35)
- Cdc42(4)
- Cdc7(3)
- Chk(13)
- c-Myc(51)
- CRM1(10)
- Cyclin-Dependent Kinases(70)
- E1 enzyme(1)
- G-quadruplex(16)
- Haspin(6)
- HMTase(1)
- Kinesin(32)
- Ksp(4)
- Microtubule/Tubulin(300)
- Mps1(17)
- Mitotic(7)
- RAD51(13)
- ROCK(76)
- Rho(13)
- PERK(21)
- PLK(51)
- PTEN(7)
- Wee1(15)
- PAK(29)
- Arp2/3 Complex(10)
- Dynamin(18)
- ECM & Adhesion Molecules(53)
- Cholesterol Metabolism(10)
- Endomembrane System & Vesicular Trafficking(34)
- G1(50)
- G2/M(35)
- G2/S(16)
- Genotoxic Stress(22)
- Inositol Phosphates(65)
- Proteolysis(179)
- Cytoskeleton & Motor Proteins(71)
- Cellular Chaperones(14)
- Cyclin G-associated Kinase (GAK)(2)
- MARK(4)
- NEKs(9)
- ATF6(2)
- ClpP(6)
- Disulfidptosis(1)
- HMG Family(1)
- PDI(1)
- SWI/SNF Complex(7)
- VISTA(4)
- HOXA(1)
Products Related to Cell Cycle/Checkpoint(1536)
- GC49344Fisetin-d5CAS: 2909407-29-8Purity: >99.00%
An internal standard for the quantification of fisetin
- GC49345Coelenterazine hcpCAS: 123437-32-1Purity: >90.00%
Coelenterazin hcp ist ein Coelenterazin-Analogon.
- GC493622-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxalineCAS: 77500-04-0Purity: >95.00%
A food-derived carcinogen
- GC49387Berberine-d6 (chloride)Purity: >99.00%
An internal standard for the quantification of berberine
- GC4939013C6-4-NitroanilineCAS: 1028361-70-7Purity: >98.00%
An internal standard for the quantification of 4-nitroaniline
- GC49393all-trans-13,14-DihydroretinolCAS: 115797-14-3Purity: >95.50%
A metabolite of all- trans retinoic acid
- GC49404Paclitaxel CCAS: 153415-45-3Purity: >95.00%
A taxoid and an inhibitor of microtubule depolymerization
- GC49412NSC 756093CAS: 1629908-92-4Purity: >98.00%
NSC 756093 ist ein potenter Inhibitor der GBP1:PIM1-Interaktion. NSC 756093 kann möglicherweise die Resistenz gegen Paclitaxel rückgängig machen. NSC 756093 kann für die Eierstockkrebsforschung verwendet werden.
- GC49419Aniline-d5CAS: 4165-61-1Purity: >99.00%
An internal standard for the quantification of aniline
- GC49430Wee1 InhibitorCAS: 622855-37-2Purity: >95.00%
Wee1 Inhibitor ist ein potenter Checkpoint-Wee1-Kinase-Inhibitor mit einem IC50 von 0,011 μM.
- GC494437α-hydroxy CholesterolCAS: 566-26-7Purity: >98.00%
7α-Hydroxycholesterin ist ein Cholesterinoxid und wird sowohl durch enzymatische als auch nicht-enzymatische Oxidation gebildet.
- GC49482(±)-Nornicotine-d4CAS: 66148-18-3Purity: >99.00%
An internal standard for the quantification of (±)-nornicotine
- GC49486Meglutol-d3CAS: 59060-36-5Purity: >99.00%
An internal standard for the quantification of meglutol
- GC49491N′-Nitrosonornicotine-d4CAS: 66148-19-4Purity: >99.00%
An internal standard for the quantification of N’-nitrosonornicotine
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49344 | Fisetin-d5 | 2909407-29-8 | >99.00% | |
An internal standard for the quantification of fisetin | ||||
| GC49345 | Coelenterazine hcp | 123437-32-1 | >90.00% | |
Coelenterazin hcp ist ein Coelenterazin-Analogon. | ||||
| GC49351 | N-Nitroso Atenolol | 134720-04-0 | >90.00% | |
A genotoxic derivative of (±)-atenolol | ||||
| GC49353 | N-Nitroso Metoprolol | 138768-62-4 | >90.00% | |
A genotoxic derivative of metoprolol | ||||
| GC49362 | 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline | 77500-04-0 | >95.00% | |
A food-derived carcinogen | ||||
| GC49387 | Berberine-d6 (chloride) | - | >99.00% | |
An internal standard for the quantification of berberine | ||||
| GC49390 | 13C6-4-Nitroaniline | 1028361-70-7 | >98.00% | |
An internal standard for the quantification of 4-nitroaniline | ||||
| GC49393 | all-trans-13,14-Dihydroretinol | 115797-14-3 | >95.50% | |
A metabolite of all- trans retinoic acid | ||||
| GC49394 | N-Nitroso Fluoxetine | 150494-06-7 | >95.00% | |
A derivative of fluoxetine | ||||
| GC49404 | Paclitaxel C | 153415-45-3 | >95.00% | |
A taxoid and an inhibitor of microtubule depolymerization | ||||
| GC49412 | NSC 756093 | 1629908-92-4 | >98.00% | |
NSC 756093 ist ein potenter Inhibitor der GBP1:PIM1-Interaktion. NSC 756093 kann möglicherweise die Resistenz gegen Paclitaxel rückgängig machen. NSC 756093 kann für die Eierstockkrebsforschung verwendet werden. | ||||
| GC49419 | Aniline-d5 | 4165-61-1 | >99.00% | |
An internal standard for the quantification of aniline | ||||
| GC49430 | Wee1 Inhibitor | 622855-37-2 | >95.00% | |
Wee1 Inhibitor ist ein potenter Checkpoint-Wee1-Kinase-Inhibitor mit einem IC50 von 0,011 μM. | ||||
| GC49437 | Gliotoxin-13C13 | - | >95.00% | |
An internal standard for the quantification of gliotoxin | ||||
| GC49443 | 7α-hydroxy Cholesterol | 566-26-7 | >98.00% | |
7α-Hydroxycholesterin ist ein Cholesterinoxid und wird sowohl durch enzymatische als auch nicht-enzymatische Oxidation gebildet. | ||||
| GC49460 | ING-2 AM | 1642554-49-1 | >90.00% | |
A cell-permeable fluorescent sodium indicator | ||||
| GC49463 | IPG-2 AM | 1369302-24-8 | >90.00% | |
A cell-permeable fluorescent potassium indicator | ||||
| GC49466 | IPG-2 TMA | 1369302-21-5 | >90.00% | |
A cell-impermeable fluorescent potassium indicator | ||||
| GC49468 | IPG-1 AM | 1369302-18-0 | >90.00% | |
A cell-permeable fluorescent potassium indicator | ||||
| GC49469 | IPG-1 TMA | 1369302-17-9 | >90.00% | |
A cell-impermeable fluorescent potassium indicator | ||||
| GC49471 | LAMP1 Monoclonal Antibody (Clone Ly1C6) | - | - | |
For immunochemical analysis of LAMP1 | ||||
| GC49482 | (±)-Nornicotine-d4 | 66148-18-3 | >99.00% | |
An internal standard for the quantification of (±)-nornicotine | ||||
| GC49486 | Meglutol-d3 | 59060-36-5 | >99.00% | |
An internal standard for the quantification of meglutol | ||||
| GC49491 | N′-Nitrosonornicotine-d4 | 66148-19-4 | >99.00% | |
An internal standard for the quantification of N’-nitrosonornicotine | ||||