DNA Damage/DNA Repair
Research Areas
- MTH1(4)
- PARP(103)
- ATM/ATR(31)
- DNA Alkylating(23)
- DNA Ligases(3)
- DNA Methyltransferase(27)
- DNA-PK(28)
- HDAC(143)
- Nucleoside Antimetabolite/Analogue(194)
- Telomerase(15)
- Topoisomerase(193)
- tankyrase(5)
- Antifolate(33)
- CDK(299)
- Checkpoint Kinase (Chk)(36)
- CRISPR/Cas9(9)
- Deubiquitinase(84)
- DNA Alkylator/Crosslinker(87)
- DNA/RNA Synthesis(575)
- Eukaryotic Initiation Factor (eIF)(33)
- IRE1(25)
- LIM Kinase (LIMK)(12)
- TOPK(6)
- Casein Kinase(59)
- DNA Intercalating Agents(8)
- DNA/RNA Oxidative Damage(13)
- Poly(ADP-ribose) Glycohydrolase (PARG)(5)
- Early 2 Factor (E2F)(2)
- Zinc Finger Protein(1)
Products Related to DNA Damage/DNA Repair(1968)
- GC790965-F-UTP trisodiumPurity: >95.00%
5-F-UTP (5-Fluorouridine-5'-triphosphate) trisodium is a monomeric raw material that can be used for nucleic acid synthesis.
- GC790975'-O-DMTr-2'-O-Me-rACAS: 103285-23-0Purity: >99.50%
5'-O-DMTr-2'-O-Me-rA is a monomeric raw material that can be used for nucleic acid synthesis.
- GC790983',5'-UpU TEACAS: 101609-06-7Purity: >98.00%
3',5'-UpU TEA (3',5'-Uridylyluridine TEA) is a 3',5'-linked uridylyluridine dinucleotide.
- GC790995'-O-DMTr-3'-O-Me-rA(Bz)CAS: 127212-38-8Purity: >98%
5'-O-DMTr-3'-O-Me-rA(Bz) is a monomeric raw material that can be used for nucleic acid synthesis.
- GC79100Morpholino G(PhAc) subunitCAS: 1044241-74-8Purity: >98%
Morpholino G(PhAc) subunit is a nucleoside analog that can be used to synthesize phosphorodiamidate morpholino oligonucleotides (PMO) [1] .
- GC79101Diguanosine 5′-triphosphate triammoniumPurity: >98.50%
Diguanosine 5′-triphosphate (Gp3G) triammonium is a dinucleoside triphosphates.
- GC79103Berzosertib hydrochlorideCAS: 1428935-04-9Purity: >98.50%
Berzosertib (VE-822) hydrochloride is an orally active, CNS-penetrant, and selective ATR kinase inhibitor.
- GC79104(Rac)-Chem-0199CAS: 122981-77-5Purity: >99.50%
(Rac)-Chem-0199 is the racemic mixture of Chem-0199.
- GC79105MDOLL-0286Purity: >99.50%
MDOLL-0286 is a selective Poly(ADP-ribose) Glycohydrolase (PARG) ( ARH3 ) inhibitor with an IC 50 of 2.3μM.
- GC79107iso-ADP ribose TEAPurity: >99.50%
iso-ADP ribose TEA is the small-molecule ligand for protein nucleic acid modification, comprising parts of two consecutive ADP-ribosyl units within the PAR chain.
- GC79113Casein Kinase II Substrate acetatePurity: >99.50%
Casein Kinase II Substrate acetate is a casein kinase II ( CK2 ) peptide substrate that can be selectively phosphorylated by CK2 [1] .
- GC79114CCK1-specific peptide substrate acetatePurity: >98.00%
CCK1-specific peptide substrate acetate is a biological active peptide.
- GC79150NV914CAS: 2341941-41-9Purity: >98.50%
NV914 is an inhibitor of FTSJ1 (tryptophan tRNA-specific 2'-O-methyltransferase) that inhibits the methyltransferase activity of FTSJ1, induces translational readthrough of premature termination codons, and enables genes carrying nonsense mutations to synthesize full-length proteins.
- GC79167METTL1-WDR4-IN-1 TFAPurity: >99.50%
METTL1-WDR4-IN-1 (Compound 1) TFA is a selective competitive inhibitor of the methyltransferase complex METTL1-WDR4 ( IC 50 =144 μM).
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC79095 | Im-GDP | 1199264-75-9 | >91.50% | |
Im-GDP is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC79096 | 5-F-UTP trisodium | - | >95.00% | |
5-F-UTP (5-Fluorouridine-5'-triphosphate) trisodium is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC79097 | 5'-O-DMTr-2'-O-Me-rA | 103285-23-0 | >99.50% | |
5'-O-DMTr-2'-O-Me-rA is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC79098 | 3',5'-UpU TEA | 101609-06-7 | >98.00% | |
3',5'-UpU TEA (3',5'-Uridylyluridine TEA) is a 3',5'-linked uridylyluridine dinucleotide. | ||||
| GC79099 | 5'-O-DMTr-3'-O-Me-rA(Bz) | 127212-38-8 | >98% | |
5'-O-DMTr-3'-O-Me-rA(Bz) is a monomeric raw material that can be used for nucleic acid synthesis. | ||||
| GC79100 | Morpholino G(PhAc) subunit | 1044241-74-8 | >98% | |
Morpholino G(PhAc) subunit is a nucleoside analog that can be used to synthesize phosphorodiamidate morpholino oligonucleotides (PMO) [1] . | ||||
| GC79101 | Diguanosine 5′-triphosphate triammonium | - | >98.50% | |
Diguanosine 5′-triphosphate (Gp3G) triammonium is a dinucleoside triphosphates. | ||||
| GC79102 | (S)-HPMPA | 92999-29-6 | >99.50% | |
(S)-HPMPA is an antiviral agent. | ||||
| GC79103 | Berzosertib hydrochloride | 1428935-04-9 | >98.50% | |
Berzosertib (VE-822) hydrochloride is an orally active, CNS-penetrant, and selective ATR kinase inhibitor. | ||||
| GC79104 | (Rac)-Chem-0199 | 122981-77-5 | >99.50% | |
(Rac)-Chem-0199 is the racemic mixture of Chem-0199. | ||||
| GC79105 | MDOLL-0286 | - | >99.50% | |
MDOLL-0286 is a selective Poly(ADP-ribose) Glycohydrolase (PARG) ( ARH3 ) inhibitor with an IC 50 of 2.3μM. | ||||
| GC79106 | FORX-428 | 2922789-15-7 | >98.00% | |
FORX-428 is an orally active, selective poly (ADP-ribose) glycohydrolase ( PARG ) inhibitor. | ||||
| GC79107 | iso-ADP ribose TEA | - | >99.50% | |
iso-ADP ribose TEA is the small-molecule ligand for protein nucleic acid modification, comprising parts of two consecutive ADP-ribosyl units within the PAR chain. | ||||
| GC79108 | AP4-43 | - | >99.50% | |
AP4-43 is an orally active CLK1, CLK4, PI3K, DDR1, EGFR and NEK4 inhibitor. | ||||
| GC79110 | CK1-IN-5 | 1000340-33-9 | >99.00% | |
CK1-IN-5 (compound B-AZ) is an inhibitor of CK1. | ||||
| GC79111 | CK2-TN03 | 313226-24-3 | >98.00% | |
CK2-TN03 is an ATP-competitive casein kinase 2 ( CK2 ) inhibitor, with an IC 50 of 165 nM and a K i of 20 nM. | ||||
| GC79112 | PF-670462 | 950980-98-0 | >99.00% | |
PF-670462 is a selective CKI ε/δ inhibitor. | ||||
| GC79113 | Casein Kinase II Substrate acetate | - | >99.50% | |
Casein Kinase II Substrate acetate is a casein kinase II ( CK2 ) peptide substrate that can be selectively phosphorylated by CK2 [1] . | ||||
| GC79114 | CCK1-specific peptide substrate acetate | - | >98.00% | |
CCK1-specific peptide substrate acetate is a biological active peptide. | ||||
| GC79121 | XL495 | 3040320-93-9 | >98% | |
XL495 is an potent, selective and orally active PKMYT1 inhibitor. | ||||
| GC79144 | MC3817 free base | - | >98% | |
MC3817 free base is a selective DNMT1 inhibitor. | ||||
| GC79145 | MC3817 | - | >99.50% | |
MC3817 is a selective DNMT1 inhibitor. | ||||
| GC79150 | NV914 | 2341941-41-9 | >98.50% | |
NV914 is an inhibitor of FTSJ1 (tryptophan tRNA-specific 2'-O-methyltransferase) that inhibits the methyltransferase activity of FTSJ1, induces translational readthrough of premature termination codons, and enables genes carrying nonsense mutations to synthesize full-length proteins. | ||||
| GC79167 | METTL1-WDR4-IN-1 TFA | - | >99.50% | |
METTL1-WDR4-IN-1 (Compound 1) TFA is a selective competitive inhibitor of the methyltransferase complex METTL1-WDR4 ( IC 50 =144 μM). | ||||
