Ac-IEPD-pNA (trifluoroacetate salt) (Synonyms: Ac-Ile-Glu-Pro-Asp-p-nitroanilide, Caspase-8 Chromogenic Substrate, Granzyme B Substrate VIII) |
Catalog No.GC40152 |
Ac-IEPD-pNA is a colorimetric substrate for granzyme B and caspase-8.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Ac-IEPD-pNA is a colorimetric substrate for granzyme B and caspase-8. Granzyme B and caspase-8 preferentially bind to and cleave the Ile-Glu-Pro-Asp (IEPD) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of granzyme B and caspase-8 activity.
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